Results 181 to 190 of about 431,462 (299)

Comparative genomics of chondrichthyan Hoxa clusters [PDF]

, 2009

core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Comparative genomics suggests extensive antithrombotic gene expansion in Haemadipsa yanyuanensis. [PDF]

BMC Genomics
Lin Y, Zhao F, Fan S, Yang D, Tong X, Tang L, Kong D, Lin G, Liu Z.   +8 more
europepmc   +1 more source

Candida: Comparative and Functional Genomics [PDF]

, 2008
Nicole Skinner
core   +2 more sources

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Large-scale phenotyping and comparative genomics reveal genetic features of Listeria persistence in epithelial cells. [PDF]

PLoS Pathog
Lotoux A, Bertrand M, Douarre PE, Kortebi M, Riveiro H, Palma F, Lakisic G, Fox EM, Guillier L, Oevermann A, Roussel S, Bierne H, Pagliuso A, Milohanic E.   +13 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Comparative genomics and biocontrol potential of five Bacillus strains isolated from grapevine rhizosphere. [PDF]

Sci Rep
Lajoinie DM, Rocco Welsh R, Rey C, Nilsson JF, Toscani AM, Djurhuus AM, Sauka D, Hansen LH, Jofré E, Pistorio M.   +9 more
europepmc   +1 more source

Comparative population genomics of crops and their wild relatives [PDF]

, 2010
Chantret, Nathalie, David, Jacques, De Kochko, Alexandre, Glemin, Sylvain, Morcillo, Fabienne, Pham, Jean Louis, Risterucci, Ange-Marie, Ruiz, Manuel, Santoni, Sylvain   +8 more
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source