Results 51 to 60 of about 663,472 (214)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Gendering Cultural Memory: Balzac’s Adieu
In this essay I examine the en-gendering of cultural memory in Honoré de Balzac´s story Adieu (1830), which proceeds from a repressed trauma originating in historical events. Balzac wrote the story in the spring of 1830, i. e.
Kristina Fjelkestam
doaj
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Life, Labor and the Picturesque:
The keynote address examines the race-gendering of Indian indentured workers in the colonial imaginary through which Jamaica was remade as a tourist destination during the late nineteenth century. It specifically examines the visual portfolio created by
Jenny Sharpe
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Kadir Dede’nin 2021’de yayımlanan Edebiyatın Ulusu: Ulusun Edebiyatı: Erken Cumhuriyet Dönemi’nde Ulus İnşası ve Roman adlı kitabı 1923-1938 arasında yayımlanmış romanların Türk ulusunun inşası için yüklendiği rolleri tartışmaktadır.
Kaan Kurt
doaj +1 more source
Safdar Hashmi’s oppositional theateris aimed at dismantling the caste, class, and gender-ridden establishment. It explores a strategic way for the establishment of a society that is free of any biases.
Vellikkeel Raghavan
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

