Results 271 to 280 of about 3,909,607 (338)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Methodological development and validation of the Thai traditional medicine-based depression care program for older adults. [PDF]

MethodsX
Nonghang S, Pakdee N, Poowanna R.
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Leveraging comparative phylogenetics for evolutionary medicine: applications to comparative oncology. [PDF]

Evol Med Public Health
Compton Mellon WJ, Sterner B, Ågren JA, Vincze O, Marx M, Kapsetaki S, Huang PH, Yavari B, McCollum HW, Natterson-Horowitz B, Human H, Baciu C, Richker H, Mallo D, Maley CC, Harmon L, Compton ZT.   +16 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

FMCL: a transformer-based feature-map classifier learning approach for enhanced brain tumor detection in MRI. [PDF]

Sci Rep
Alanazi TM.
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Costoclavicular Brachial Plexus Block for Upper Limb Procedures: A Narrative Review of Efficacy and Safety. [PDF]

Cureus
Kewalramani R, Vaswani A, Bairwa K, Munavalli R, Bhati SK.   +4 more
europepmc   +1 more source

A novel leaf counting method for field tobacco plants based on UAV imagery and an improved PointNext. [PDF]

Sci Rep
Nan D, Li J, Liang H, Feng Z, Tong W, Bi Y, Liu R.   +6 more
europepmc   +1 more source

Survival Modeling Using Deep Learning, Machine Learning, and Statistical Methods: A Comparative Analysis for Predicting Mortality After Hospital Admission. [PDF]

Health Data Sci
Wang Z, Lee JW, Chakraborty T, Ning Y, Liu M, Xie F, Ong MEH, Liu N.   +7 more
europepmc   +1 more source