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Comparative Effectiveness Questions in Oncology

New England Journal of Medicine, 2014
High prices for cancer drugs preclude independent comparative effectiveness trials that would seek to establish equally effective but cheaper alternatives — thereby protecting the market share of expensive drugs. How can we make progress toward conducting such trials?
Sham, Mailankody, Vinay, Prasad
openaire   +2 more sources

Feline mammary tumours in comparative oncology

Journal of Dairy Research, 2005
Naturally occurring tumours in domestic animals have been recognized as an interesting opportunity for comparative oncology (MacEwen, 1990; Vail & MacEwen, 2000). Cancer is the second most frequent cause of death in humans and the first one in dogs and cats (Jemal et al. 2003).
ZAPPULLI, VALENTINA ELENA GIUDITTA   +4 more
openaire   +3 more sources

Comparative Evaluation of LLMs in Clinical Oncology

NEJM AI
As artificial intelligence (AI) tools become widely accessible, more patients and medical professionals will turn to them for medical information. Large language models (LLMs), a subset of AI, excel in natural language processing tasks and hold considerable promise for clinical use.
Nicholas R. Rydzewski   +6 more
openaire   +2 more sources

Implications of comparative effectiveness research for radiation oncology

Practical Radiation Oncology, 2011
The essence of comparative effectiveness research (CER) is to understand what health interventions work, for which patients, and under what conditions. The objective of this article is to introduce the relative strengths and weaknesses of several forms of evidence to illustrate the potential for CER evidence generation within radiation oncology.We ...
Justin E, Bekelman   +2 more
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Comparative Effectiveness Research: Opportunities in Surgical Oncology

Seminars in Radiation Oncology, 2014
Comparative effectiveness research (CER) is especially applicable to surgical oncology because of the numerous challenges associated with conducting surgical randomized controlled trials, and the opportunity to apply various CER methodologies to answer surgical questions. In this article, several past randomized trials or attempted trials are described
Heather B, Neuman, Caprice C, Greenberg
openaire   +2 more sources

Canine comparative oncology for translational radiation research

International Journal of Radiation Biology, 2021
Laboratory and clinical research are essential for advancing radiation research; however, there is a growing awareness that conventional laboratory animal models and early-phase clinical studies in patients have not improved the low success rates and late-stage failures in new cancer therapy efforts.
openaire   +2 more sources

Comparative Oncology of Skin Cancer

2013
Studying the naturally occurring skin cancers seen in companion (pet) animals provides an opportunity to improve our knowledge about the biology, epidemiology, pathogenesis, and treatment of skin cancer across species, contributing to advances in human and animal health through a comparative oncology approach.
openaire   +1 more source

A Systematic Review of Rehabilitation and Exercise Recommendations in Oncology Guidelines

Ca-A Cancer Journal for Clinicians, 2021
Julie K. Silver   +2 more
exaly  

Modern Developments in Germline Pharmacogenomics for Oncology Prescribing

Ca-A Cancer Journal for Clinicians, 2022
Natalie Reizine, Peter H O'Donnell
exaly  

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