Results 81 to 90 of about 3,258,123 (297)

Comparative evaluation of oncologic outcomes in colon cancer [PDF]

Acta Cirurgica Brasileira, 2016
In this paper we report clinical variables on colon cancer series. Oncological outcomes were compared to low-income and high-income countries.We analysed a prospective database of 51 colon cancer patients submitted to primary tumor resection between 2010 and 2011, showing clinical variables and oncologic outcomes.R0 resection obtained in 80.4%, 21.6 ...
Bernardes, Mário Vinícius Angelete Alvarez, Feitosa, Marley Ribeiro, Peria, Fernanda Maris, Tirapelli, Daniela Pretti da Cunha, Rocha, José Joaquim Ribeiro da, Feres, Omar   +5 more
openaire   +5 more sources

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Cadmium and cancer: A study on canine tumours and environmental bioindicators (Sus scrofa)

Ecotoxicology and Environmental Safety
Pets (i.e., dogs and cats) due to their spontaneous tumour development in shared environments with humans and their genetic, immunological, and molecular similarities, serve as valuable comparative oncology models.
Filippo Dell’Anno, Roberta Giugliano, Livia De Paolis, Ines Crescio, Elisabetta Razzuoli   +4 more
doaj   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Mortality and heavy metals environmental exposure: a study in dogs

Frontiers in Veterinary Science
IntroductionDogs are human companions and share environmental conditions with their owners. Epidemiological studies have shown that dogs seem to be good sentinel animals for the association of diseases and/or mortality provoked by chronic exposure to ...
Roberta Giugliano, Maria Ines Crescio, Valeria Cosma, Valentina Ciccotelli, Barbara Vivaldi, Elisabetta Razzuoli   +5 more
doaj   +1 more source

Comparative Aspects of Osteosarcoma Pathogenesis in Humans and Dogs

Veterinary Sciences, 2015
Osteosarcoma (OS) is a primary and aggressive bone sarcoma affecting the skeleton of two principal species, human beings and canines. The biologic behavior of OS is conserved between people and dogs, and evidence suggests that fundamental discoveries in ...
Timothy M. Fan, Chand Khanna
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

DNA Polymerase Eta Stabilizes Mutant p53 Protein to Increase Tumor Cell Growth

Cells
DNA polymerase eta (PolH) is a specialized translesion synthesis DNA polymerase that enables replication across damaged DNA and contributes to cellular tolerance of genotoxic stress.
Jin Zhang, Yang Shi, Xinbin Chen
doaj   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

The European Society for Medical Oncology (ESMO) Precision Medicine Glossary

, 2017
Precision medicine is rapidly evolving within the field of oncology and has brought many new concepts and terminologies that are often poorly defined when first introduced, which may subsequently lead to miscommunication within the oncology community ...
Soria, J. C, Marais, R, Normanno, N, J. Rodon, Le Tourneau, C, C. Swanton, R. Marais, Campbell, P, Swanton, C, Michiels, S, Yates, L. R, Scarpa, A, J. Seoane, P. Campbell, N. Normanno, L.R. Yates, S. Michiels, F. Andre, L.L. Siu, A. Scarpa, Seoane, J, J.C. Soria, J.S. Reis-Filho, Reis-filho, J. S, Rodon, J, Andre, F., C. Le Tourneau, Siu, L. L, Marais, Richard, Soria, J, Andre, F, Yates, L, Siu, L, Reis-Filho, J   +33 more
core   +1 more source