Results 121 to 130 of about 1,391,767 (243)

Limitations of <i>p</i> ₅₀ as a measure of seed longevity in comparative studies and the way forward. [PDF]

Appl Plant Sci
Klepka L, Carta A, Hay FR, Bucharova A.
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Canine and feline mesenchymal stem cells: an integrative review of direct comparative studies by species and tissue source. [PDF]

J Vet Sci
Kim HS, Shin TH.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Comment on "The Critical Omission of CRRT Dose in Comparative Studies of RRT Modalities for Sepsis-Associated AKI". [PDF]

JA Clin Rep
Okano H, Okamoto H, Tanaka H, Sakurai R, Yamazaki T.   +4 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Comparative Studies of Different Ablation Techniques for Atrial Fibrillation. [PDF]

Rev Cardiovasc Med
Keževičiūtė M, Marinskis G, Sudavičienė D, Barysienė J, Bileišienė N, Radauskaitė G, Aidietis A, Račkauskas G.   +7 more
europepmc   +1 more source

Atherosclerosis: A Comparative Study [PDF]

BMJ, 1962
R, FINLAYSON, C, SYMONS, R N, FIENNES
openaire   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Efficacy and safety of tranexamic acid during bariatric surgery: an updated systematic review and meta-analysis of 10 comparative studies. [PDF]

BMC Surg
Abu-Zaid A, Alotaibi MK, Hasan FN, Alkandari HA, Almutawtah S, Almutawaa BN, Alajmi MS, Aladwani FN, Alselahy LA, Ali FA, Alblooshi SS, Alfayadh HM, Alharran AM.   +12 more
europepmc   +1 more source