Results 101 to 110 of about 45,735 (284)
The new international classification of gymnosperms is adduce in the publication. This classification was proposed by the group of scientists with registration of the analysis of DNA structure, morphological, phylogenetics and other investigations ...
S.I. Kuznetsov +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Jalons pour des études comparatives en musique entre France et Espagne au XVIIe siècle
Les études comparatives en musique se heurtent à un double défi qui n’a jamais été pleinement résolu. Celui de la langue de réflexion – et de rédaction – sur les sources documentaires d’une part et, d’autre part, celui du langage même de la musique.
Louis Jambou
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Anticorps monoclonaux anti-IgGs de zébu. Réactivités comparatives
En utilisant des anticorps monoclonaux (Amclx) anti-IgGs de zébu, plusieurs sortes d'épitopes ont pu être identifiés : spécifiques du zébu, communs au zébu et au boeuf, au zébu et au mouton ou aux trois espèces.
C. Atrax, E. Nakounne, J. Vincent
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
On the Social Diffusion of Comparative Forms in English Historical Correspondence
The historical trajectory of English adjective comparison has sparked an interest in historical linguistics through corpus-based research. Nevertheless, this issue has been relatively unexplored through a historical sociolinguistic approach, specifically
Tamara García-Vidal
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

