Results 111 to 120 of about 14,581 (303)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Vocalic elements and prosody in Slavic comparatives

open access: yes, 2017
The first part of the article deals with the ablaut pattern(s) that may be reconstructed on the basis of Slavic comparatives. It is claimed that three separate morphological categories (including comparatives) support the interpretation of the vowel o in
Rafał Szeptyński
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

On the Social Diffusion of Comparative Forms in English Historical Correspondence

open access: yesAtlantis
The historical trajectory of English adjective comparison has sparked an interest in historical linguistics through corpus-based research. Nevertheless, this issue has been relatively unexplored through a historical sociolinguistic approach, specifically
Tamara García-Vidal
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Comparatives

open access: yes
Students are given jumbled sentences and they need to put them in the correct order to make a coherent text. Then, they focus on the comparative forms in the text and compare them with a grammar section which provides them with an overview of ...
Milovic, Dragan
core  

Comparatives and quantifiers [PDF]

open access: yes, 2008
A traditional issue in the analysis of comparatives is whether or not degrees are essential. In the first part of this paper I discuss the traditional analyses that account for comparatives with (Seuren, von Stechow) and without (Klein) degrees, and ...
van Rooij, R.
core  

A Note on Phrasal Comparatives

open access: yes, 2012
This paper investigates the various comparative operators that a language might employ and provides arguments for choosing a particular one. In particular, different phrasal comparatives are contrasted.
Beck, Sigrid   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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