Results 71 to 80 of about 136,452 (263)

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato   +27 more
wiley   +1 more source

Bio‐Inspired Biopolymeric Implantable Platform for Localized and Sustained Drug Delivery in Solid Tumor Treatment

open access: yesAdvanced Functional Materials, EarlyView.
A bio‐inspired biopolymeric implantable drug delivery platform enables localized and sustained release of 7‐ethyl‐10‐hydroxycamptothecin (SN‐38) in solid tumor treatment. The three‐dimensional (3D) structured crosslinked‐chitosan implants are fabricated via 3D‐printed molds and provide drug release over 3 months, significantly inhibiting tumor growth ...
Mercedes Lozano‐Garcia   +12 more
wiley   +1 more source

Biomimetic Microfractals Based Flexible Triboelectric Nanogenerators

open access: yesAdvanced Functional Materials, EarlyView.
A leaf‐skeleton‐based microfractal architecture is integrated with guided CuNW networks and biomimetic triboelectric polymer layers, enabling breathable, flexible, and material‐efficient triboelectric nanogenerators. The resulting system combines enhanced charge generation and charge transport, offering potential for next‐generation self‐powered ...
Amit Barua   +7 more
wiley   +1 more source

Developing, Piloting and Evaluating a Patient Support Portal for Men With Prostate Cancer in Victoria: An Action Research Study

open access: yesHealth Expectations
Introduction Men with prostate cancer (PCa) and their support providers face challenges in accessing high‐quality, impartial information tailored to their specific needs to enhance their overall care and decision‐making.
Benjamin Shemesh   +14 more
doaj   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

open access: yesAdvanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim   +9 more
wiley   +1 more source

A Review on Fundamentals of Noise-Shaping SAR ADCs and Design Considerations

open access: yesChips
A general overview of Noise-Shaping Successive Approximation Register (SAR) analog-to-digital converters is provided, encompassing the fundamentals, operational principles, and key architectures of Noise-Shaping SAR (NS SAR).
Victor H. Arzate-Palma   +3 more
doaj   +1 more source

A Low-Power High-Speed Dynamic Comparator With a Transconductance-Enhanced Latching Stage

open access: yesIEEE Access, 2019
Low-power, high-speed dynamic comparators are highly desirable in the design of high-speed analog-to-digital converters (ADC) and digital I/O circuits. Most dynamic comparators use a pair of cross-coupled inverters as the latching stage, which provides ...
Yao Wang   +5 more
doaj   +1 more source

Neuromorphic Electronics for Intelligence Everywhere: Emerging Devices, Flexible Platforms, and Scalable System Architectures

open access: yesAdvanced Materials, EarlyView.
The perspective presents an integrated view of neuromorphic technologies, from device physics to real‐time applicability, while highlighting the necessity of full‐stack co‐optimization. By outlining practical hardware‐level strategies to exploit device behavior and mitigate non‐idealities, it shows pathways for building efficient, scalable, and ...
Kapil Bhardwaj   +8 more
wiley   +1 more source

An Unbalanced Clock Based Dynamic Comparator: A High-Speed Low-Offset Design Approach for ADC Applications

open access: yesAdvances in Electrical and Electronic Engineering, 2019
Currently, dynamic comparator approach necessitates in high-speed and power efficient analog-to-digital converter applications due to its high latching speed and ultra-low power consumption. In this paper, a~novel dynamic comparator is proposed to reduce
Vikrant Varshney, Rajendra Kumar Nagaria
doaj   +1 more source

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