Results 91 to 100 of about 17,626,989 (327)
Let X be any algebraic variety over \({\mathbb{C}}\). Then there is in a natural way associated to X a complex analytic space \(X_{an}\). Also for every coherent algebraic sheaf F on X there is an associated coherent analytic sheaf \(F_{an}\) on \(X_{an}\), and one has comparison maps \(\alpha_ i: H^ i(X,F)\to H^ i(X_{an},F_{an})\) on cohomology.
openaire +4 more sources
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
The principal result in this note is the following: If \[ \int^{(b/2)+h}_{(b/2)-h}[p(x)-(\pi^ 2/b^ 2)]dx\geq 0 \] for each h ...
openaire +3 more sources
Comparison of Invariant Metrics [PDF]
We estimate the boundary behavior of the Kobayashi metric on $\C\sm\set{0,1}$. We also compare the Bergman metric on the ring domain in $\C^{2}$ to the Bergman metric on the ball.Comment: submitted.
Kang, Hyunsuk+2 more
core
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
O objetivo deste artigo é descrever problematizando o cotidiano da construção de uma pesquisa que, ela mesma, busca entender como se produz, a partir da implantação de políticas públicas, ações sobre um cotidiano naturalizado de discriminações de caráter
Henrique Caetano Nardi
doaj +1 more source
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
wiley +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling+4 more
wiley +1 more source