Results 91 to 100 of about 89,195 (253)

Peroxisomes: A New Hub for Metabolic Engineering in Yeast

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Natalja Kulagina   +3 more
doaj   +1 more source

Requirements for software engineering languages [PDF]

open access: yes, 1985
This paper analyzes the concepts of software construction embodied in the Draco system. The analysis relates specific mechanisms in Draco to particular software engineering (SE) principles and suggests future research needed to extend the approach.
Freeman, Peter, Staa, Arndt von
core   +1 more source

Horizontal transfer between loose compartments stabilizes replication of fragmented ribozymes

open access: yes, 2019
The emergence of replicases that can replicate themselves is a central issue in the origin of life. Recent experiments suggest that such replicases can be realized if an RNA polymerase ribozyme is divided into fragments short enough to be replicable by ...
Kamimura, Atsushi   +3 more
core   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Human intraovarian interleukin-1 (IL-1) system: highly compartmentalized and hormonally dependent regulation of the genes encoding IL-1, its receptor, and its receptor antagonist. [PDF]

open access: bronze, 1992
Arye Hurwitz   +9 more
openalex   +1 more source

Compartmentalization and Aggregation of Biomolecular Condensates in Crowded Hydrogels for Enhanced Nucleic Acid Diagnosis

open access: yesAdvanced Science
Membrane‐less compartments, such as biomolecular condensates, play a crucial role in cellular organization by enhancing enzymatic reaction efficiency through compartmentalization and crowding.
Fangbin Xiao   +3 more
doaj   +1 more source

Autopoiesis Concepts for Chemical Origins of Life and Synthetic Biology [Stenogram of the popular lecture on the foreign bibliographic seminar] [PDF]

open access: yes, 2017
The monograph (Luisi P.L. "The Emergence of Life: From Chemical Origins to Synthetic Biology", 2010, Cambridge University Press, Cambridge, New York etc., 315 p.) is a well-written, informative book providing a novel view on the interrelation between the
Gradoff, Olle
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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