Results 31 to 40 of about 89,195 (253)
Barriers in the Brain: Resolving Dendritic Spine Morphology and Compartmentalization
Frontiers in Neuroanatomy, 2014 Dendritic spines are micron-sized protrusions that harbor the majority of excitatory synapses in the central nervous system. The head of the spine is connected to the dendritic shaft by a 50-400 nm thin membrane tube, called the spine neck, which has ...
Max eAdrian +5 more
doaj +1 more source
cAMP signaling in blood platelets - old friends and new players.
Frontiers in Pharmacology, 2015 Atherothrombosis, the pathology underlying numerous cardiovascular diseases, is a major cause of death globally. Hyperactive blood platelets play a key role in the atherothrombotic process through the release of inflammatory mediators and formation of ...
Zaher eRaslan, Khalid M Naseem
doaj +1 more source
Tropical Medicine and Infectious DiseaseNeurocognitive impairment is an important cause of HIV-associated morbidity. The advent of antiretroviral therapy (ART) has shifted the spectrum of HIV-associated cognitive impairment from HIV-associated dementia to milder forms of cognitive impairment ...
Sophie H. Kelly +3 more
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Nanoclustering as a dominant feature of plasma membrane organization [PDF]
, 2014 Early studies have revealed that some mammalian plasma membrane proteins exist in small nanoclusters. The advent of super-resolution microscopy has corroborated and extended this picture, and led to the suggestion that many, if not most, membrane ...
Cambi, Alessandra +4 more
core +5 more sources
Intestinal stem cell proliferation and epithelial homeostasis in the adult Drosophila midgut [PDF]
, 2015 Adult tissue homeostasis requires a tight balance between the removal of old or damaged cells and the production of new ones. Such processes are usually driven by dedicated stem cells that reside within specific tissue locations or niches.
Carroll, Lynsey +2 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Acta Scientiarum: Biological Sciences, 2012 The present study examined the behavior of a reservoir located on subtropical latitude (Dona Francisca reservoir). The limnological variables measured were dissolved oxygen, temperature, pH and electric conductivity.
Maria Angélica Oliveira +2 more
doaj +3 more sources
Subcellular Compartmentalization of Glucose Mediated Insulin Secretion
CellsRegulation of blood glucose levels depends on the property of beta cells to couple glucose sensing with insulin secretion. This is accomplished by the concentration-dependent flux of glucose through glycolysis and oxidative phosphorylation, generating ...
Zhongying Wang +4 more
doaj +1 more source
Production of the Fragrance Geraniol in Peroxisomes of a Product-Tolerant Baker’s Yeast
Frontiers in Bioengineering and Biotechnology, 2020 Monoterpenoids, such as the plant metabolite geraniol, are of high industrial relevance since they are important fragrance materials for perfumes, cosmetics, and household products.
Jennifer Gerke +10 more
doaj +1 more source
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source