Results 51 to 60 of about 222,490 (305)
Compassionate use of tocilizumab in severe SARS-CoV2 pneumonia
International Journal of Infectious Diseases, 2021 Introduction: Tocilizumab (TCZ) is an interleukin-6 receptor antagonist, which has been used for the treatment of severe SARS-CoV-2 pneumonia (SSP), which aims to ameliorate the cytokine release syndrome (CRS) induced acute respiratory distress syndrome (
Miguel Górgolas Hernández-Mora +27 more
doaj +1 more source
ASPETTI REGOLATORI SULL'USO TERAPEUTICO DEI FARMACI: IL CASO DEL SOFOSBUVIR E DEL NIVOLUMAB [PDF]
, 2015 The purpose of this Thesis is the discussion about regulatory aspects of "compassionate use" of drugs and in particular the relative Italian regulations and necessary procedures to apply them correctly (for example, important documents to be submitted to
CORVAGLIA, LOUIS GIUSEPPE
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Compassionate drug use: Current status in India
Perspectives in Clinical Research, 2020 The World Health Organization defines compassionate use (CU) as a "program that is intended to provide potentially life-saving experimental treatments to patients suffering from a disease for which no satisfactory authorized therapy exists and/or who cannot enter a clinical trial.
Shetty, Yashashri C. +2 more
openaire +2 more sources
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
Palliative Care and Social Practice, 2023 Background: Compassionate communities build on health promoting palliative care that aims to address gaps in access, quality, and continuity of care in the context of dying, death, loss, and grief. While community engagement is a core principle of public
Émilie Lessard +10 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg +20 more
wiley +1 more source
LifeAntimicrobial resistance is a global threat to public health. The growing resistance of bacteria to commonly used antibiotics necessitates the search for and development of alternative treatments.
Jörg Eschweiler +6 more
doaj +1 more source
Stemming the Tide: Strategies to Reduce the Growth and Cut the Cost of the Federal Prison System [PDF]
, 2013 The federal prison population has escalated from under 25,000 inmates in 1980 to over 219,000 today. This growth has come at great expense to taxpayers and other important fiscal priorities.
Julie Samuels +2 more
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Arthritis Care &Research, Accepted Article.Objectives This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah +6 more
wiley +1 more source