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The United States Food and Drug Administration and Prescription Drug Promotion. [PDF]
J Innov Card Rhythm Manag, 2019 The impact of prescription drug promotion on health-care professionals (HCPs) is significant. Pharmaceutical industry spending on promotion to HCPs greatly outpaces spending on direct-to-consumer promotion. According to Syneos Health™ PromotionalAnswers, in 2017, the pharmaceutical industry spent more than $24 billion on drug promotion, with more than $
Kalola AS, Dean R.
europepmc +4 more sources
Frontiers in Microbiology, 2021 Salmonella enterica is a significant and phylogenetically diverse zoonotic pathogen. To understand its genomic heterogeneity and antimicrobial resistance, we performed long-read sequencing on Salmonella isolated from retail meats and food animals.
Cong Li +9 more
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Characterization of Biofilm Formation by Mycobacterium chimaera on Medical Device Materials
Frontiers in Microbiology, 2021 Non-tuberculous mycobacteria (NTM) are widespread in the environment and are a public health concern due to their resistance to antimicrobial agents. The colonization of surgical heater-cooler devices (HCDs) by the slow-growing NTM species Mycobacterium ...
Archana D. Siddam +6 more
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Unapproved drugs in the united states and the food and drug administration [PDF]
Advances in Therapy, 2011 Despite more than a century of evolving federal legislation, there remain many unapproved drugs on the United States (US) market. This article reviews the history of drug approval in the US, beginning with the landmark Pure Food and Drug Act of 1906, through to the development of the US Food and Drug Administration (FDA).
Nasr, Alexander +2 more
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Frontiers in Microbiology, 2023 Most current Salmonella subtyping analyses rely on whole genome sequencing (WGS), which focuses on the high-resolution analysis of single genomes or multiple single genomes from the isolated colonies on microbiological agar plates.
Kranti Konganti +12 more
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Machine learning models for rat multigeneration reproductive toxicity prediction
Frontiers in Pharmacology, 2022 Reproductive toxicity is one of the prominent endpoints in the risk assessment of environmental and industrial chemicals. Due to the complexity of the reproductive system, traditional reproductive toxicity testing in animals, especially guideline ...
Jie Liu +6 more
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Development of QSAR models to predict blood-brain barrier permeability
Frontiers in Pharmacology, 2022 Assessing drug permeability across the blood-brain barrier (BBB) is important when evaluating the abuse potential of new pharmaceuticals as well as developing novel therapeutics that target central nervous system disorders.
Sadegh Faramarzi +5 more
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High-Resolution Microbiome Profiling for Detection and Tracking of Salmonella enterica
Frontiers in Microbiology, 2017 16S rRNA community profiling continues to be a useful tool to study microbiome composition and dynamics, in part due to advances in next generation sequencing technology that translate into reductions in cost.
Christopher J. Grim +5 more
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Frontiers in Microbiology, 2022 Low moisture foods (LMFs) have traditionally been recognized as safe for consumption, as most bacteria require higher water content to grow. However, outbreaks due to LMF foods are increasing, and the microbial pathogen Salmonella enterica is frequently ...
Cary P. Davies +7 more
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A Comparison of Pediatric and Adult Safety Studies for Antipsychotic and Antidepressant Drugs Submitted to the United States Food and Drug Administration. [PDF]
J Pediatr, 2019 Liu XI +9 more
europepmc +2 more sources