Results 151 to 160 of about 165,938,772 (216)

Effects of extraction solvents on the recovery of bioactive compounds from Platycladus orientalis Leaves of different tree ages: a comparative metabolomics approach. [PDF]

BMC Plant Biol
Li H, Cui B, Zhao H, Wang G, Wang Y, Zhang S.   +5 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

The Eighth Day of Creation: looking back across 40 years to the birth of molecular biology and the roots of modern cell biology. [PDF]

Mol Biol Cell, 2020
Peifer M.
europepmc   +1 more source

Is Yuan in China's Three Gorges a Gibbon or a Langur? [PDF]

Int J Primatol, 2022
Niu K, Ang A, Xiao Z, Gamba M.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Research and validation of forest carbon sequestration measurement model based on biomass method-A case study of Guizhou Province. [PDF]

PLoS One
Min Z, Yang W, Yan Q, Jun Y, Chunling L, Rui RW.   +5 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Integrated Education Models for Addressing Substance Use Among Schoolchildren: A Scoping Review of School-Based Educational Interventions. [PDF]

Int J Environ Res Public Health
Bajpai Tewari D, Gautam U, Jaiswal V, Pooja, Mishra A, Das P.   +5 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Analysis of medieval burials from Ibiza reveals genetic and pathogenic diversity during the Islamic period. [PDF]

Nat Commun
Rodríguez-Varela R, Pochon Z, Mas-Sandoval A, Yaka R, Fortes-Lima CA, García Rubio A, Márquez-Grant N, Marí J, Graziani G, Ferrer Abárzuza A, Vicente M, Lorca-Francisco L, Linderholm A, Lagerholm VK, Arauna LR, Pérez-Ramallo P, Krzewińska M, Schlebusch CM, Götherström A.   +18 more
europepmc   +1 more source