Results 41 to 50 of about 533,078 (303)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Transylvanian Review of Administrative SciencesThe size of the public sector in the economy is closely related to globalization. It aims to maximize welfare. There are two main hypotheses (efficiency and compensation) discussed in the literature on this relationship.
Deniz Aytaç
doaj +1 more source
The Induced Productivity Decline Hypothesis: More Physicians, Higher Compensation and Fewer Services
Healthcare Policy | Politiques de Santé, 2021 Public outrage regarding physician shortages during the past two decades have led to policies aimed at significantly increasing physician supply, yet access remains elusive. In this paper, we examine this puzzling trend and the causes underlying it by analyzing physician supply, compensation and productivity and the reasons behind productivity decline.
Lee, Shoo K. +2 more
openaire +3 more sources
ENGARUH KOMPENSASI DAN SEMANGAT KERJA TERHADAP PRODUKTIVITAS KERJA KARYAWAN P.T. ORGANIK ALAM LESTARI PURWOREJO [PDF]
, 2008 Generally every company will always try to increase its productivity. The purposes of its productivity are to increase material efficiency, reduce cost of production and optimizing time output.
ANUGRAHANI, SHINTHA
core
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, 2012 Background: There is still a question of whether online friendship predicts changes in face-to-face friendship (Reduction Hypothesis) or face-to-face friendship predicts changes in online friendship (Compensation Hypothesis) during adolescence.
Zucchetti Giulia +2 more
doaj +1 more source
Frontiers in Psychiatry, 2018 In 1939, the Penrose hypothesis suggested that the number of psychiatric hospital beds was inversely related to the size of prison populations. Central to a causal interpretation of the Penrose hypothesis is the idea that a small proportion of any ...
Sebastian Schildbach, Carola Schildbach
doaj +1 more source
Contribution of Workload and Compensation to Teacher's Burnout
Al-Ishlah: Jurnal Pendidikan, 2021 This research was conducted to show the contribution of workload and compensation to teacher burnout in Cilacap Regency. The methodology in this study is the quantitative approach with multiple linear regression models.
Masduki Ahmad, Heni Rochimah
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source