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An ATP7A‐Mediated Endogenous Regulation Bio‐Clay Enzyme Enables Self‐Amplified Copper Accumulation for Immunogenic Pyrop

open access: yesAdvanced Science, EarlyView.
A self‐amplifying bio‐clay nanozyme (Bio‐Clayzyme) disrupts tumor metabolic homeostasis through endogenous copper transporter ATPase (ATP7A) downregulation, enhancing cascade catalysis and triggering immunogenic pyroptosis for effective tumor immunotherapy.
Weimin Xie   +4 more
wiley   +1 more source
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Modelling Compensatory Growth

Functional Ecology, 1994
1. We formulate a simple, physiologically based model to investigate the phenomenon of compensatory growth. 2. The model is based upon two key assumptions. First, that an individual partitions net assimilate between two tissue types: those which can and those which cannot be remobilized once laid down.
Broekhuisen, N.   +3 more
openaire   +2 more sources

Mechanisms of reduced and compensatory growth

Domestic Animal Endocrinology, 2000
Growth is an integrated process, resulting from the response of cells dependent on the endocrine status and nutrient availability. During feed restriction, the production and secretion of growth hormone (GH) by the pituitary gland are enhanced, but the number of GH receptors decreases.
Hornick, Jean-Luc   +4 more
openaire   +2 more sources

Kinetics of Compensatory Growth

The Quarterly Review of Biology, 1965
Growth in tissues and organs can be stimulated by either partial ablation or increased demands for physiological activity. Both causes appear to operate via identical pathways whereby the mounting requirements for extra functional output stimulate DNA replication and concomitantly promote specific protein synthesis.
openaire   +2 more sources

Compensatory growth in sheep

Australian Journal of Agricultural Research, 1979
Some attributes of the body composition of Dorset Horn x Merino wethers, which were either continuously grown or subjected to one or two periods of starvation-weight loss, realimentation and compensatory growth, were studied. Periods of restricted feed intake were imposed when liveweights were either below (23 kg) or above (43 kg) the level generally ...
RF Thornton, RL Hood, PN Jones, VM Re
openaire   +1 more source

Compensatory Growth of the Kidney

New England Journal of Medicine, 1969
COMPARED with the intense restorative activity in liver after a major resection,1 compensation seems indolent in the kidney deprived of its counterpart.
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PHYSIOLOGICAL COSTS OF COMPENSATORY GROWTH IN A DAMSELFLY

Ecology, 2006
Little is known about physiological costs of rapid growth. We successfully generated compensatory growth to time stress and transient food stress in the damselfly Lestes viridis and studied the physiological correlates of the resulting reduced ability to cope with starvation.
Robby, Stoks   +2 more
openaire   +2 more sources

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