Results 41 to 50 of about 52,823 (219)

Quines competències professionals ha de tenir un mestre avui?

open access: yesRevista Catalana de Pedagogia, 2016
Per concretar les competències professionals d’algú que es vulgui dedicar a l’educació, cal tenir present quines finalitats volem que tingui l’acció educativa i quin és l’horitzó de sentit que volem assolir.
Jaume Cela i Ollé   +1 more
doaj  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Perfils professionals i gestió per competències a les biblioteques públiques

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2003
Les competències professionals lligades als perfils professionals és un concepte que s’està imposant amb força tant en el món laboral com en el de l’ensenyament superior.
Salvador Ugalde, Lluís
doaj  

Identification of core competencies for exercise oncology professionals: A Delphi study of United States and Australian participants

open access: yesCancer Medicine
Introduction Integration of exercise into standard oncology care requires a highly skilled workforce of exercise professionals; however, competency requirements have not kept pace with advancements in the field.
Mary A. Kennedy   +8 more
doaj   +1 more source

Evaluating the Effectiveness of an Online Course on Pediatric Malnutrition for Syrian Health Professionals: Qualitative Delphi Study

open access: yesJMIR Medical Education
BackgroundThere is a shortage of competent health professionals in managing malnutrition. Online education may be a practical and flexible approach to address this gap.
Amal Sahyouni   +2 more
doaj   +1 more source

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

open access: yesAdvanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua   +6 more
wiley   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

open access: yesAdvanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing   +10 more
wiley   +1 more source

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

open access: yesAdvanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu   +10 more
wiley   +1 more source

Interfacial Control in Cu–MXene Hybrids Enables Selective NOx‐to‐NH3 Electroconversion: A Critical Review

open access: yesAdvanced Science, EarlyView.
Cu‐MXene interfacial catalysts provide a promising platform for electrochemical NOx upcycling to ammonia. The synergy between Cu active sites and conductive, surface‐tunable MXene supports promotes NOx adsorption, intermediate stabilization, and selective NH3 formation while suppressing competing hydrogen evolution, offering a route toward sustainable ...
Hafiz Muhammad Adeel Sharif   +5 more
wiley   +1 more source

A Delphi study on health literacy competencies for health professionals

open access: yesBMC Medical Education
Background Health professionals play a key role in promoting health literacy, as they continue to be one of the main points of contact and most trusted source of information for healthcare users on questions and concerns regarding health and disease.
Anna-Sophia Beese   +3 more
doaj   +1 more source

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