Results 121 to 130 of about 16,483,093 (330)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

The use of ICT tools by academic teachers in the international comparative context [PDF]

, 2019
The article sets out to analyze the professional competencies on the standard European e-Competence Framework. The survey of information technology teachers of Ukrainian universities concerning the necessity of forming and development of European e ...
Cubo-Delgado, S, Morze, Nataliia, Noskova, Tetiana, Pavlova, Tatiana, Yakovleva, Olga   +4 more
core  

Digital Competence of Educators (DigCompEdu): Development and Evaluation of a Self-assessment Instrument for Teachers' Digital Competence

International Conference on Computer Supported Education, 2019
Based on the European Framework for the Digital Competence of Educators (DigCompEdu), a selfassessment tool was developed to measure teachers’ digital competence. This paper describes the DigCompEdu reference framework, the development and the evaluation
M. Ghomi, Christine Redecker
semanticscholar   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

Cultural competency in the delivery of health services for Indigenous people [PDF]

, 2015
Aim and objectives This review aims to examine available evidence on cultural competence in health care settings to identify key approaches and strategies that can contribute to improving the development and implementation of Indigenous health services ...
Anton Clifford, Janya McCalman, Komla Tsey, Roxanne Bainbridge   +3 more
core   +2 more sources

Early signatures of regime shifts in gene expression dynamics

, 2013
Recently, a large number of studies have been carried out on the early signatures of sudden regime shifts in systems as diverse as ecosystems, financial markets, population biology and complex diseases.
Bose, Indrani, Ghosh, Sayantari, Pal, Amit Kumar, Pal, Mainak   +3 more
core   +1 more source

Transcript profiling for early stages during embryo development in Scots pine [PDF]

, 2016
Background: Characterization of the expression and function of genes regulating embryo development in conifers is interesting from an evolutionary point of view.
Abrahamsson, Malin, Canovas, Francisco, Craven-Bartle, Blanca, Merino, Irene, Sterck, Lieven, von Arnold, Sara   +5 more
core   +2 more sources

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

The ParB-parS Chromosome Segregation System Modulates Competence Development in Streptococcus pneumoniae

mBio, 2015
ParB proteins bind centromere-like DNA sequences called parS sites and are involved in plasmid and chromosome segregation in bacteria. We previously showed that the opportunistic human pathogen Streptococcus pneumoniae contains four parS sequences ...
L. Attaiech, A. Minnen, Morten Kjos, S. Gruber, J. Veening   +4 more
semanticscholar   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source