Results 121 to 130 of about 1,202,597 (408)

How an online questionnaire can explore leadership teaching in an undergraduate curriculum. [PDF]

open access: yes, 2012
OBJECTIVES: To design a tool to explore current leadership teaching in an undergraduate curriculum, using the medical leadership competency framework (MLCF) DESIGN: An online questionnaire was designed based on the MLCF competences and sent to all ...
Bicknell, C   +3 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Regional odontodysplasia: a report of unusual case with in-depth analysis

open access: yesJournal of Oral Biology and Craniofacial Research
Background/purpose: Regional odontodysplasia (RO) is a rare developmental anomaly affecting dental tissue formation, typically confined to a single quadrant.
Charles Béhot   +6 more
doaj   +1 more source

Diversity of human capital attributes and diversity of remunerating systems [PDF]

open access: yes
This paper aims at comparing the respective impact of the traditional Human Capital Variables (HCV) and of competences explicitly assessed on employees' remuneration.
Fatima Suleman, Jean-Jacques Paul
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

A European research agenda for lifelong learning [PDF]

open access: yes, 2008
It is a generally accepted truth that without a proper educational system no country will prosper, nor will its inhabitants. With the arrival of the post-industrial society, in Europe and elsewhere, it has become increasingly clear that people should ...
Boon, Jo   +7 more
core   +2 more sources

Describing Papers and Reviewers' Competences by Taxonomy of Keywords

open access: yes, 2012
This article focuses on the importance of the precise calculation of similarity factors between papers and reviewers for performing a fair and accurate automatic assignment of reviewers to papers. It suggests that papers and reviewers' competences should
Kalmukov, Yordan
core   +1 more source

Digital Literacy Circulation: Adolescents and Flows of Knowledge about New Media [PDF]

open access: yes, 2016
The aim of this paper is to discuss the output of an empirical research on digital skills in order to develop a typology of skills circulation among young digital users.
Riva, Claudio, Scarcelli, Cosimo Marco
core   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

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