Results 191 to 200 of about 454,455 (258)

Parental Competencies as Familial Protective Factors in Adolescent Substance Use Prevention: A Scoping Review. [PDF]

Children (Basel)
Hong KY, Shin J.
europepmc   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

Localizing the main components of competencies in high-level managers based on health system evaluation indicators: Content analysis approach. [PDF]

J Educ Health Promot
Foladi SH, Ferdousi M, Afshar MT, Sepehr P, Dehghan P, Safdarian A, Karimi V.   +6 more
europepmc   +1 more source

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source

Experiences of Healthcare Professionals in Home Based-Caring for Children With Type 1-Diabetes in Vulnerable Positions: A Qualitative Study. [PDF]

Scand J Caring Sci
Jeppesen MN, Clemensen J, Heidemann MS, Hertz B, Rasmussen B, Rothmann MJ.   +5 more
europepmc   +1 more source

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

Assessing Oral Health Literacy in Children and Adolescents: Current Evidence, Measurement Gaps, and Developmental Considerations. [PDF]

Children (Basel)
Özşin Özler C, Güçiz Doğan B.
europepmc   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

A Workforce-Informed Competency Framework Defines 30 Core Abilities of Veterinary Diagnostic Imaging Specialists. [PDF]

Vet Radiol Ultrasound
Noyes JA, Brisson J, Buckley GJ, Hammond L, Manzi T, Pollard RE, Sage J, Waller KR, Welch P.   +8 more
europepmc   +1 more source