Results 201 to 210 of about 132,789 (268)

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

Advanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng, Jiahao Lin, Qiushuang Zhang, Xiangdong Zhang, Yicong Dai, Jinghong Li   +5 more
wiley   +1 more source

Paramedics: A Missing Workforce in Australia's Mental Health System. [PDF]

Aust J Rural Health
Emond K, Spong J.
europepmc   +1 more source

COMPETENCE AND COMPETENCY: CONSENSUS

"Scientific notes of the University"KROK", 2019
openaire   +2 more sources

The Third‐Generation Magnetic Super‐Stable Mineralizer: Complete Removal and Separation of Multiple Heavy Metal Pollutants

Advanced Science, EarlyView.
The 3rd‐generation magnetic super‐stable mineralizer M‐MgAl‐700 features a core‐shell structure, strong superparamagnetism, large surface area, and abundant oxygen defects. It achieves exceptional Cd(II) and As(V) mineralization capacities, reducing both pollutants in co‐contaminated water and soil to meet national standards.
Haoran Wang, Menghan Huang, Ruihua Mao, Xiaohan Zhang, Zhaohui Wu, Xiaofeng Pang, Tong Lin, Dongyuan Cui, Sai An, Yu‐Fei Song   +9 more
wiley   +1 more source

Socioemotional Competencies of Primary Education Teachers and Their Relationship with Attitudes Toward Inclusive Education. [PDF]

Behav Sci (Basel)
Albalá Genol MÁ, Messina Albarenque C, Gómez Yepes T, Etchezahar E.   +3 more
europepmc   +1 more source

Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound

Advanced Science, EarlyView.
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García, José A. Pineda‐Pardo, Inés Trigo‐Damas, Marta Gutiérrez, Marta Castillo‐Ortiz, Megan Carrillo, Alejandro Reinares‐Sebastian, Víctor Medina‐Chavarrías, Itay Rachmilevitch, Masahiko Takada, José A. Obeso, Javier Blesa   +11 more
wiley   +1 more source

Building managerial competence in nurse unit managers: insights from a qualitative study. [PDF]

BMC Nurs
Lee J, Kim M.
europepmc   +1 more source

A Biomimetic Nanoparticle System Intercepts and Degrades Thrombospondin‐1 to Restore Vascular Homeostasis After Ischemic Injury

Advanced Science, EarlyView.
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang, Xiandi Meng, Yanbao Xin, Kuirong Mao, Huizhu Tan, Changkai Ma, Xiuxiu Cong, Mengfei Zhao, Meiling Yu, Si Chen, Yue Hou, Yong‐Guang Yang, Tianmeng Sun   +12 more
wiley   +1 more source

Evaluating Patient Safety Competency Acquisition Through Clinical Simulation: Development and Application of the Clinical Simulation Learning Patient Safety Scale. [PDF]

Nurs Res Pract
Ramírez-Baraldes E, García-Gutiérrez D, Romero-Saldaña M, Diez-Caballero BR, González-Moret R, Picher-Martínez M, García-Salido C.   +6 more
europepmc   +1 more source

Caring for the allergic patient - WAO White Book on Allergy 2026 - 1. [PDF]

World Allergy Organ J
Gerth van Wijk R.
europepmc   +1 more source