Results 61 to 70 of about 1,605,625 (404)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Why is it so hard to improve physicians’ health? A qualitative interview study with senior physicians on mechanisms inherent in professional identity

open access: yesGMS Journal for Medical Education
Objectives: Current research increasingly describes physicians’ health as endangered. Interventions to improve physicians’ health show inconsistent results. In order to investigate possible causes for weak long-term effects, we examined senior physicians'
Schulte, Heike   +2 more
doaj   +1 more source

The Efficacy and Development of Students' Problem-Solving Strategies During Compulsory Schooling: Logfile Analyses

open access: yesFrontiers in Psychology, 2018
The purpose of this study was to examine the role of exploration strategies students used in the first phase of problem solving. The sample for the study was drawn from 3rd- to 12th-grade students (aged 9–18) in Hungarian schools (n = 4,371).
Gyöngyvér Molnár, Benő Csapó
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Religious competence as cultural competence [PDF]

open access: yesTranscultural Psychiatry, 2012
Definitions of cultural competence often refer to the need to be aware and attentive to the religious and spiritual needs and orientations of patients. However, the institution of psychiatry maintains an ambivalent attitude to the incorporation of religion and spirituality into psychiatric practice.
openaire   +2 more sources

The Competencies, Roles and Scope of Practice of Advanced Psychiatric Nursing in Indonesia [PDF]

open access: yes, 2013
The graduate advanced psychiatric nursing (psychiatric nursing specialist) from master degree in Indonesia are about 70 nurses, 67 nurses were graduated from University of Indonesia.
Wardani, Y. (Yulia)
core  

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Cardiac Auscultation Lab Using a Heart Sounds Auscultation Simulation Manikin

open access: yesMedEdPORTAL, 2019
Introduction Cardiac auscultation skills are essential to the development of a competent physician. We created a hypothesis-driven cardiac auscultation laboratory session utilizing a high-fidelity simulator to teach these skills to second-year medical ...
Antonia Quinn   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A Systematic Literature Review of 21st Century Skills and Competencies in Primary Education

open access: yesInternational Journal of Instruction, 2018
The current literature review the discussion of 21st century skills in the context of primary education. A sample of texts satisfying the predetermined inclusion criteria was analyzed (n=40), with the aims of synthesizing the proposed frameworks that are
Areti Chalkiadaki
semanticscholar   +1 more source

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