Results 61 to 70 of about 1,466,248 (386)

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Why is it so hard to improve physicians’ health? A qualitative interview study with senior physicians on mechanisms inherent in professional identity

GMS Journal for Medical Education
Objectives: Current research increasingly describes physicians’ health as endangered. Interventions to improve physicians’ health show inconsistent results. In order to investigate possible causes for weak long-term effects, we examined senior physicians'
Schulte, Heike, Lutz, Gabriele, Kiessling, Claudia   +2 more
doaj   +1 more source

Cardiac Auscultation Lab Using a Heart Sounds Auscultation Simulation Manikin

MedEdPORTAL, 2019
Introduction Cardiac auscultation skills are essential to the development of a competent physician. We created a hypothesis-driven cardiac auscultation laboratory session utilizing a high-fidelity simulator to teach these skills to second-year medical ...
Antonia Quinn, Jennifer Kaminsky, Andrew Adler, Shirley Eisner, Robin Ovitsh   +4 more
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Model of professional retraining of teachers based on the development of STEM competencies [PDF]

, 2018
The article describes a methodology for organizing lifelong learning, professional retraining of teachers in STEM field and their lifelong learning in Volodymyr Hnatiuk Ternopil National Pedagogical University (Ukraine).
Balyk, Nadiia, Barna, Olga, Oleksiuk, Vasyl, Shmyger, Galina   +3 more
core  

A Delphi study to validate competency-based criteria to assess undergraduate midwifery students' competencies in the maternity ward [PDF]

, 2017
Background: workplace learning plays a crucial role in midwifery education. Twelve midwifery schools in Flanders (Belgium) aimed to implement a standardised and evidence-based method to learn and assess competencies in practice. This study focuses on the
Embo, Mieke, Helsloot, K, Michels, N, Valcke, Martin   +3 more
core   +2 more sources

Circular Economy Competencies for Design

Sustainability, 2020
This study addresses what competencies (knowledge, skills, and attitudes) designers need in order to successfully design products and services for a circular economy.
D. Sumter, Jotte de Koning, C. Bakker, R. Balkenende   +3 more
semanticscholar   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Electronic Portfolio as a Mean of Reflection Formation for Students Learning

Psihologo-Pedagogičeskie Issledovaniâ, 2021
The article presents the results of a study aimed at the reflection formation of students to the educational program they are mastering as a program of preparation for professional activity through a specially organized educational environment, including
Margolis A.A., Safronova M.A., Drobyazko A.A., Kuravsky L.S., Golovanova I.A., Pominov D.A.   +5 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source