Results 151 to 160 of about 23,722,999 (291)

The Development of an Instructional-Design Model for Competency-based University Education

Journal of Lifelong Learning Society, 2023
Minhyo Lee, Changwoo Nam
openaire   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

Leveraging AI to Accelerate Competency-Based Education in the Health Professions. [PDF]

Perspect Med Educ
Lomis KD, Pusic MV, Warm E, Busari JO, Huwendiek S, Incoll IW, Lau LST, Boscardin CK, Chen JH, Tanaka P, Hauer KE, As members of the International Competency-Based Health Professions Educators Collaborative.   +11 more
europepmc   +1 more source

Competency-based training: adult unemployed students` perspectives in Certificate IV in Small Business Management (NEIS)

, 2001
Competency-based training: adult unemployed students` perspectives in Certificate IV in Small Business Management ...
Derek Kosbab (13050462)
core  

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

The Faculty Development Paradox: Applying Competency-Based Education Principles to Faculty Development. [PDF]

Perspect Med Educ
Turner TL, Karpinski J, Damodaran AK, Tanaka P, Chan MK, Pinilla S, Richardson D, Goldhamer MEJ, Snell L, Edgar L, As members of the International Competency-Based Health Professions Education Collaborators.   +10 more
europepmc   +1 more source

Competency-Based Education: Aligning Instructional Practices as Viewed by Teachers

This study explored teachers' experiences in aligning instructional practices with the principles of Competency-Based Education (CBE) within the school setting. Specifically, it aimed to examine how teachers adapt their teaching strategies to meet CBE expectations and identify their coping mechanisms when addressing implementation challenges.
openaire   +2 more sources

SynNotch Receptors for Visualizing Immunoreceptor Force Transmission and Downstream Signaling In Vivo

Advanced Science, EarlyView.
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li, Jintian Lyu, Kaitao Li, Ameya Dravid, Deepali Balasubramani, Amir H. K. Ashkezari, Hyun‐Kyu Choi, Gabriel A. Kwong, Ankur Singh, Cheng Zhu   +9 more
wiley   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

The Educational Alliance: Essential to Implement Competency-Based Health Professions Education. [PDF]

Perspect Med Educ
Hauer KE, Goldhamer MEJ, Amiel J, Richardson D, Schwartz A, Marty AP, Molgaard L, Pinilla S, Breckwoldt J, As members of the International Competency-Based Health Professions Educators Collaborative.   +9 more
europepmc   +1 more source