Results 191 to 200 of about 1,232,754 (357)

Hierarchical Regulatory Networks Reveal Conserved Drivers of Plant Drought Response at the Cell‐Type Level

open access: yesAdvanced Science, EarlyView.
This study presents a comprehensive multi‐omics framework to uncover cell‐type‐specific regulatory networks in plant drought responses. By integrating transcriptomic, proteomic, and epigenetic data from nearly 30 000 samples, key regulators such as CIPK23 and NLP7 are identified, revealing insights into conserved drought tolerance mechanisms and ...
Moyang Liu   +9 more
wiley   +1 more source

Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong   +17 more
wiley   +1 more source

The Achieved Capabilities Questionnaire for Community Mental Health (ACQ‐CMH): A consumer‐based measure for the evaluation of community mental health interventions

open access: yesAmerican Journal of Community Psychology, Volume 70, Issue 3-4, Page 327-339, December 2022., 2022
Abstract The capabilities approach offers a multidimensional, ecological, and agent‐centered framework that may inspire models of intervention and evaluation. A growing number of measures grounded on the capabilities approach for outcome measurement are appearing.
Beatrice Sacchetto   +2 more
wiley   +1 more source

DNA repair in Bacillus subtilis: excision repair capacity of competent cells [PDF]

open access: bronze, 1979
Ronald E. Yasbin   +2 more
openalex   +1 more source

Structural and Biochemical Characterization of a Widespread Enterobacterial Peroxidase Encapsulin

open access: yesAdvanced Science, EarlyView.
Encapsulins are self‐assembling bacterial protein compartments loaded with cargo enzymes. The most abundant encapsulin cargo class are Dye‐decolorizing Peroxidases (DyPs). In this study, we structurally and biochemically characterize a DyP encapsulin found in many enterobacteria.
Natalia C. Ubilla‐Rodriguez   +2 more
wiley   +1 more source

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