Results 21 to 30 of about 333,512 (299)

Inovasi Pelayanan pada Organisasi Publik

Jurnal Wacana Kinerja, 2023
Dalam era keterbukaan informasi dan revolusi industri 4.0, inovasi dalam pelayanan publik menjadi isu strategis. Pemanfaatan teknologi IoT memberikan kesempatan bagi masyarakat untuk dengan mudah memperoleh informasi dan layanan publik. Organisasi publik
Hendra Nugroho Saputro
doaj  

Cardiac competency statements: time for a refresh

, 2021
Liz Butterfield and Mary Kirk discuss the need to update cardiac competency statements for ...
Butterfield, Liz, Kirk, Mary, Mary Kirk, Liz Butterfield   +3 more
core   +1 more source

Standardised Versioning of Datasets: a FAIR–compliant Proposal

Scientific Data
This paper presents a standardised dataset versioning framework for improved reusability, recognition and data version tracking, facilitating comparisons and informed decision-making for data usability and workflow integration.
Alba González–Cebrián, Michael Bradford, Adriana E. Chis, Horacio González–Vélez   +3 more
doaj   +1 more source

Decentralization and Governance in Indonesia

Jurnal Wacana Kinerja, 2021
Dua dekade lebih telah menjadi jangka waktu terlaksananya desentralisasi di Indonesia sejak disahkannya Undang-Undang No. 22 tahun 1999. Banyak studi telah mengevaluasi berbagai sisi dari desentralisasi di Indonesia seperti dampak desentralisasi fiskal ...
Pratiwi Pratiwi
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The Interplay Between Vitamin D Deficiency, Iron Status, and Anemia Risk in Moroccan Women of Reproductive Age: A Cross-Sectional Analysis

Epidemiologia
Background: Vitamin D and iron deficiencies are prevalent among Moroccan women of reproductive age (WRA). Research suggests that Vitamin D deficiency (VDD) may impair iron bioavailability, potentially leading to iron deficiency (ID) and anemia ...
Noura Zouine, Ilham Lhilali, Lode Godderis, Adil El Midaoui, Samir El Jaafari, Younes Filali-Zegzouti   +5 more
doaj   +1 more source