Results 41 to 50 of about 143,281 (266)

Resensi: SDGs Desa, Percepatan Pencapaian Tujuan Pembangunan Nasional Berkelanjutan

open access: yesJurnal Wacana Kinerja, 2021
Buku “SDGs Desa Percepatan Pencapaian Tujuan Pembangunan Nasional Berkelanjutan” ini menyuguhkan gagasan baru dari A. Halim Iskandar selaku Menteri Desa, Pembangunan Daerah Tertinggal dan Transmigrasi tentang konsep Sustainable Development Goals ...
Rosita Novi Andari
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Efektivitas Implementasi Pelayanan Publik Digital: Studi Kasus Pelayanan Perpustakaan Digital Puslatbang PKASN LAN

open access: yesJurnal Wacana Kinerja, 2022
One of Puslatbang PKASN LAN’s digital services is the library application which started in 2010. This application was developed internally and has been used for more than a decade.
Yuyu Yuningsih
doaj  

Obesity education for front-line healthcare providers

open access: yesBMC Medical Education, 2018
Background To assess the effect of an interprofessional educational activity on professional skills, attitudes, and perceived challenges toward obesity management among front-line healthcare providers.
Diana C. Sanchez-Ramirez   +3 more
doaj   +1 more source

Children’s Participation: Questioning Competence and Competencies?

open access: yesSocial Inclusion, 2017
While Article 12 of the Convention on the Rights of the Child has encouraged children’s participation in collective decision-making, the literature is replete with the challenges as well as successes of such participation. One challenge is adults’ perceptions of children’s competence and competencies. These are frequently used as threshold criteria, so
Le borgne, Carine   +1 more
openaire   +3 more sources

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Implementasi e-learning di Masa Pandemi Covid-19: Studi Kasus pada Latsar CPNS di Puslatbang PKAN LAN

open access: yesJurnal Wacana Kinerja, 2021
Perkembangan teknologi yang pesat mendorong terjadinya perubahan di berbagai aspek kehidupan. Salah satunya di dunia pendidikan dan pelatihan, di mana model pembelajaran yang sebelumnya banyak dilakukan di dalam kelas (klasikal) atau luar jaringan ...
Yuyu Yuningsih
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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