Results 131 to 140 of about 2,386,609 (293)

Truthful Mechanisms for Competing Submodular Processes

, 2012
The latest version contains a revised Section 4 and Appendix ...
Borodin, Allan, Braverman, Mark, Lucier, Brendan, Oren, Joel   +3 more
openaire   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands. [PDF]

Nat Genet, 2021
Weinberg DN, Rosenbaum P, Chen X, Barrows D, Horth C, Marunde MR, Popova IK, Gillespie ZB, Keogh MC, Lu C, Majewski J, Allis CD.   +11 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Modeling Competing Line-broadening Mechanisms in Neutron Star Atmospheres: Interference between Motional Stark and Ion Broadening

The Astrophysical Journal
Neutron star surfaces have extremely high magnetic fields. In the atmosphere, the broadening of spectral lines will be substantial from the dense plasma as well as from the magnetic field.
Thomas A. Gomez, Mark C. Zammit, Igor Bray, Christopher J. Fontes, Jackson R. White, Harold Johnson   +5 more
doaj   +1 more source

Particle currents and the distribution of terrace sizes in unstable epitaxial growth

, 2001
A solid-on-solid model of epitaxial growth in 1+1 dimensions is investigated in which slope dependent upward and downward particle currents compete on the surface.
A. Pimpinelli, J. Krim, J. Villain, J. Wollschläger, J.G. Amar, J.W. Evans, L. Golubovic, M. Ahr, M. Biehl, M. Biehl, M. Kinne, M. Rost, M. Siegert, M.A. El-Shehawey, O. Pierre-Louis, P. Politi, P. Smilauer, S. Schinzer, S. Schinzer, S. Schinzer, W. Kinzel, Y. Yue   +21 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Trading Mechanism Selection with Directed Search when Buyers are Risk Averse [PDF]

We endogenize the trading mechanism selection in a model of directed search with risk averse buyers and show that the unique symmetric equilibrium entails all sellers using fixed price trading.
Selcuk, Cemil
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Dynamic performance of TCP over optical burst-switched networks

Tongxin xuebao, 2007
Performances of different TCP implementations deployed in OBSN under dynamic competing traffic were compared.The elapsed time taken to transfer a fix-sized file was selected as the metric.In addition,the internal mechanisms of burst drops and cause for ...
LUO Jiang-tao, CHANG Hao, XIA Da, ZHANG Zhi-zhong   +3 more
doaj   +2 more sources