Results 81 to 90 of about 2,386,609 (293)

A Simple Generative Model of Collective Online Behaviour [PDF]

, 2013
Human activities increasingly take place in online environments, providing novel opportunities for relating individual behaviours to population-level outcomes. In this paper, we introduce a simple generative model for the collective behaviour of millions
Cellai, Davide, Gleeson, James P., Onnela, Jukka-Pekka, Porter, Mason A., Reed-Tsochas, Felix   +4 more
core   +1 more source

Mitochondria-driven cell elongation mechanism for competing sperms [PDF]

Fly, 2012
Sexual competition has selected a number of extreme phenotypes like the tail ornament of peacock male. Sperm tail of Drosophilidae elongate up to 6 cm as a result of evolutionary selection for reproductive fitness among competing sperms. Sperm elongation takes place post meiotically and can proceed in the absence of an axoneme.
Noguchi, Tatsuhiko, Koizumi, Michiko, Hayashi, Shigeo   +2 more
openaire   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Identification of competing neural mechanisms underlying positive and negative perceptual hysteresis in the human visual system

NeuroImage, 2020
Hysteresis is a well-known phenomenon in physics that relates changes in a system with its prior history. It is also part of human visual experience (perceptual hysteresis), and two different neural mechanisms might explain it: persistence (a cause of ...
Alexandre Sayal, Teresa Sousa, João V. Duarte, Gabriel N. Costa, Ricardo Martins, Miguel Castelo-Branco   +5 more
doaj   +1 more source

A competing risk joint model for dealing with different types of missing data in an intervention trial in prodromal Alzheimer’s disease

Alzheimer’s Research & Therapy, 2021
Background Missing data can complicate the interpretability of a clinical trial, especially if the proportion is substantial and if there are different, potentially outcome-dependent causes.
Floor M. van Oudenhoven, Sophie H. N. Swinkels, Hilkka Soininen, Miia Kivipelto, Tobias Hartmann, Dimitris Rizopoulos, on behalf of the LipiDiDiet clinical study group   +6 more
doaj   +1 more source

Influence of friction on granular segregation [PDF]

, 2007
Vertical shaking of a mixture of small and large beads can lead to segregation where the large beads either accumulate at the top of the sample, the so called Brazil Nut effect (BNE), or at the bottom, the Reverse Brazil Nut effect (RBNE).
Schröter, Matthias, Swinney, Harry L., Ulrich, Stephan   +2 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Supply Chain Integration Capability, Intra-Cluster Co-Opetition Strategy, and Breakthrough Innovation: The Moderating Effect of Environmental Turbulence

Systems
Under the frequent occurrence of external environmental risks and in the context of breakthrough innovations driving new quality productivity, this study explores the intrinsic mechanisms by which supply chain integration affects enterprise breakthrough ...
Jianping Wang, Senqiang Wang
doaj   +1 more source

Homogeneity trend on social networks changes evolutionary advantage in competitive information diffusion

New Journal of Physics, 2020
Competitive information diffusion on large-scale social networks reveals fundamental characteristics of rumor contagions and has profound influence on public opinion formation.
Longzhao Liu, Xin Wang, Yi Zheng, Wenyi Fang, Shaoting Tang, Zhiming Zheng   +5 more
doaj   +1 more source

A Novel Immune-Related Competing Endogenous RNA Network Predicts Prognosis of Acute Myeloid Leukemia

Frontiers in Oncology, 2020
BackgroundAcute myeloid leukemia (AML) is a genetically, biologically and clinically heterogeneous hematopoietic malignancy that is highly dependent on the bone marrow (BM) microenvironment.
Shujuan Wang, Lu Yang, Yajun Liu, Yan Xu, Danfeng Zhang, Zhongxing Jiang, Chong Wang, Yanfang Liu   +7 more
doaj   +1 more source