Results 31 to 40 of about 476,100 (264)

Estimation of Employee Turnover with Competing Risks Models

open access: yesFolia Oeconomica Stetinensia, 2015
Employee turnover accompanies every business organization, regardless of the industry and size. Nowadays, many companies struggle with problems related to the lack of sufficient information about the nature of employee turnover processes.
Grzenda Wioletta, Buczyński Michał K.
doaj   +1 more source

Risks, risk assessment and risk competence in toxicology

open access: yesGerman medical science : GMS e-journal, 2015
Das Verständnis der toxischen Wirkungen von Stoffen setzt ein gutes Verständnis der Physiologie bzw. Biochemie voraus. Das häufig beschriebene mangelnde Verständnis in der Bevölkerung für die Pharmakologie und Toxikologie beruht deshalb zu einem großen Teil auf den mangelnden Kenntnissen der erforderlichen Grundlagen.
Stahlmann, R, Horvath, A
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

COMPARISON BETWEEN COMPETING RISKS VIA THE COPULA-GRAPHIC ESTIMATOR COMPARACIÓN ENTRE RIESGOS COMPETITIVOS VÍA EL ESTIMADOR CÓPULA-GRÁFICO

open access: yesRevista Colombiana de Estadística, 2011
The identifiability problem in competing risks associated to the dependence measure between the failure modes, can be solved by means of the copula-graphic estimator which assumes the copula function known. This paper compares, through a simulation study,
Yáñez Sergio   +3 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Comparación entre riesgos competitivos vía el estimador cópula-gráfico

open access: yesRevista Colombiana de Estadística, 2011
En riesgos competitivos, el problema de identificabilidad asociado a la dependencia entre los modos de falla, se puede resolver utilizando el estimador cópula-gráfico que asume la forma de la cópula conocida.
SERGIO YÁÑEZ   +3 more
doaj  

Estimating restricted mean survival time and expected life-years lost in the presence of competing risks within flexible parametric survival models

open access: yesBMC Medical Research Methodology, 2021
Background Royston-Parmar flexible parametric survival models (FPMs) can be fitted on either the cause-specific hazards or cumulative incidence scale in the presence of competing risks.
Sarwar I. Mozumder   +2 more
doaj   +1 more source

Target Trial Emulation Using Hospital-Based Observational Data: Demonstration and Application in COVID-19

open access: yesLife, 2023
Methodological biases are common in observational studies evaluating treatment effectiveness. The objective of this study is to emulate a target trial in a competing risks setting using hospital-based observational data. We extend established methodology
Oksana Martinuka   +8 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

APPLICATION OF THE RECURRENT DATA ANALYSIS ON FL245 SWITCHES AT INTERCONEXIÓN ELÉCTRICA S.A. APLICACIÓN DEL ANÁLISIS DE DATOS RECURRENTES SOBRE INTERRUPTORES FL245 EN INTERCONEXIÓN ELÉCTRICA S.A.

open access: yesRevista Colombiana de Estadística, 2011
Recurrent data arise when a unit (or group of such units) is monitored over time and a particular event (or group of events) occurs at several points of the observation period, for example, times of recurrent episodes of a disease in patients or times of
Lopera Carlos M., Manotas Eva Cristina
doaj  

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