Results 41 to 50 of about 2,145,607 (256)

A genome-wide association study on hematopoietic stem cell transplantation reveals novel genomic loci associated with transplant outcomes

open access: yesFrontiers in Immunology
IntroductionData on genomic susceptibility for adverse outcomes after hematopoietic stem cell transplantation (HSCT) for recipients are scarce.MethodsWe performed a genome wide association study (GWAS) to identify genes associated with survival/mortality,
Albert Rosenberger   +8 more
doaj   +1 more source

Dipolar Tree Ensemble With and Without Adjustment to Competing Risks: Application to Medical Data

open access: yesStudies in Logic, Grammar and Rhetoric, 2013
The analysis of survival data often aims at the prediction of failure time distribution. In cases of competing risk events, the time distributions of more than one failure are under investigation.
Krętowska Małgorzata
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Comparación entre riesgos competitivos vía el estimador cópula-gráfico

open access: yesRevista Colombiana de Estadística, 2011
En riesgos competitivos, el problema de identificabilidad asociado a la dependencia entre los modos de falla, se puede resolver utilizando el estimador cópula-gráfico que asume la forma de la cópula conocida.
SERGIO YÁÑEZ   +3 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Long-term absenteeism due to sickness in Sweden. How long does it take and what happens after? [PDF]

open access: yes, 2007
Long-term sickness, Returns to work, Full and partial disability, Competing-risks model, Multinomial-logit model, I12, J21, J28,
Daniela Andrén   +2 more
core   +1 more source

APPLICATION OF THE RECURRENT DATA ANALYSIS ON FL245 SWITCHES AT INTERCONEXIÓN ELÉCTRICA S.A. APLICACIÓN DEL ANÁLISIS DE DATOS RECURRENTES SOBRE INTERRUPTORES FL245 EN INTERCONEXIÓN ELÉCTRICA S.A.

open access: yesRevista Colombiana de Estadística, 2011
Recurrent data arise when a unit (or group of such units) is monitored over time and a particular event (or group of events) occurs at several points of the observation period, for example, times of recurrent episodes of a disease in patients or times of
Lopera Carlos M., Manotas Eva Cristina
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Statistical analysis and application of competing risks model with regression

open access: yesCroatian Operational Research Review, 2019
The paper deals with the methods of statistical analysis of dependent competing risks in the presence of covariates. The problem of identification of marginal and joint distributions of competing random variables is recalled and certain ...
Petr Volf
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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