Results 111 to 120 of about 2,429,852 (338)

Use of sigma factor M from Bacillus subtilis in the development of an orthogonal expression system in Escherichia coli [PDF]

open access: yes, 2014
Background: Technological advances in synthetic biology, systems biology, and metabolic engineering have boosted applications of industrial biotechnology for an increasing number of complex and high added-value molecules.
Bervoets, Indra   +2 more
core  

Female Fighting and Host Competition Among Four Sympatric Species of \u3ci\u3eMelittobia\u3c/i\u3e (Hymenoptera: Eulophidae) [PDF]

open access: yes, 2018
Melittobia is a genus of parasitic wasps well known for high levels of inbreeding and violent male combat. Casual observations of groups of sisters of M.
Deyrup, Leif D, Matthews, Robert W
core   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

An integrated engineering worldview of synthetic biology education through the lens of webinar based pedagogy

open access: yesFrontiers in Bioengineering and Biotechnology
Synthetic biology is an interdisciplinary field that brings together engineering and biology concepts alongside the arts and social sciences to develop solutions to pressing problems in our world.
Iain George   +9 more
doaj   +1 more source

Il fiore e la biologia fiorale [PDF]

open access: yes, 2011
Floral biology includes the series of processes which leads buds to evolve into flowers and fruits. Improving the knowledge on floral biology in olive is important both for scientific understanding and for practical reasons, since optimizing these ...
Caporali, Silvia   +4 more
core  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Estimating the Effect of Competition on Trait Evolution Using Maximum Likelihood Inference.

open access: yesSystematic Biology, 2016
Many classical ecological and evolutionary theoretical frameworks posit that competition between species is an important selective force. For example, in adaptive radiations, resource competition between evolving lineages plays a role in driving ...
J. Drury   +3 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Darwinian Adverse Selection

open access: yes, 2015
We develop a model to study the role of rationality in economics and biology. The model's agents differ continuously in their ability to make rational choices.
Kuhle, Wolfgang
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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