Results 121 to 130 of about 2,429,852 (338)
Deutsche Zeitschrift für Sportmedizin, 2016 We assessed whetherthe seasonal training pattern of endurance athletes produces corresponding adaptations of mitochondrial, angiogenic, and myogenic processes in skeletal muscle and whether these relate to the training volume and metabolic load during ...
Frese S +12 more
doaj +1 more source
Improving deconvolution methods in biology through open innovation competitions: an application to the connectivity map [PDF]
, 2021 Andrea Blasco +11 more
openalex +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Germination Biology and the Ecology of Annual Plants [PDF]
, 1992 We derive spatially explicit population models for the interaction between a species of annual plant and a community of perennial species. The models are used to explore the conditions for persistence of the annual in both a constant and a stochastic ...
Long, M.J., Rees, M.
core
Modelling and measuring intracellular competition for finite resources during gene expression
Journal of the Royal Society Interface, 2019 Dissecting the competition between genes for shared expressional resources is of fundamental importance for understanding the interplay between cellular components.
R. Sabi, T. Tuller
semanticscholar +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
The Role of Synthetic Biology in NASA's Missions [PDF]
The time has come to for NASA to exploit the nascent field of synthetic biology in pursuit of its mission, including aeronautics, earth science, astrobiology and notably, human exploration.
Rothschild, Lynn J.
core +1 more source
A two-strain ecoepidemic competition model
, 2014 In this paper we consider a competition system in which two diseases spread by contact. We characterize the system behavior, establishing that only some configurations are possible.
Cavoretto, Roberto +3 more
core +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source