Results 121 to 130 of about 2,456,397 (363)
Estimating the Effect of Competition on Trait Evolution Using Maximum Likelihood Inference.
Systematic Biology, 2016 Many classical ecological and evolutionary theoretical frameworks posit that competition between species is an important selective force. For example, in adaptive radiations, resource competition between evolving lineages plays a role in driving ...
J. Drury +3 more
semanticscholar +1 more source
Coexistence and relative abundance in annual plant assemblages: The roles of competition and colonization [PDF]
, 2002 Although an interspecific trade-off between competitive and colonizing ability can permit multispecies coexistence, whether this mechanism controls the structure of natural systems remains unresolved.
Levine, J.M., Rees, M.
core
Drosophila as a model system to study nonautonomous mechanisms affecting tumour growth and cell death [PDF]
, 2018 The study of cancer has represented a central focus in medical research for over a century. The great complexity and constant evolution of the pathology require the use of multiple research model systems and interdisciplinary approaches.
Cordero, Julia B. +2 more
core +3 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Grand challenges for the spatial information community
Journal of Spatial Information Science, 2020 The spatial information (SI) community has an opportunity to address major societal and scientific problems including public health, climate change, air pollution, transportation, and others. Beyond the significant contributions made by the SI community,
Leye Wang, Ouri Wolfson
doaj +1 more source
, 2015 We develop a model to study the role of rationality in economics and biology. The model's agents differ continuously in their ability to make rational choices.
Kuhle, Wolfgang
core
Effects of temporal variability on rare plant persistence in annual [PDF]
, 2004 Traditional conservation biology regards environmental fluctuations as detrimental to persistence, reducing long-term average growth rates and increasing the probability of extinction.
Levine, J.M., Rees, M.
core
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Partial Differential Equations in Applied MathematicsPrey–predator models play a vital role in mathematical biology. The competition that evolves between them is addressed in a broad scenario. According to genetics theory, various specie’s genotypes yield different outcomes in competition.
G. Santhosh Kumar +4 more
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source