Ejaculate Investment in a Promiscuous Rodent, \u3cem\u3ePeromyscus maniculatus\u3c/em\u3e: Effects of Population Density and Social Role [PDF]
, 2006 Questions: How does average male investment in ejaculates vary with changing population density (and thus with the risk of sperm competition) in a promiscuous species? Do individual male investment strategies vary with population density?
Long, Tristan A.F., Montgomerie, Robert
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Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Divergent Biosynthesis of C-Nucleoside Minimycin and Indigoidine in Bacteria
iScience, 2019 Summary: Minimycin (MIN) is a C-nucleoside antibiotic structurally related to pseudouridine, and indigoidine is a naturally occurring blue pigment produced by diverse bacteria.
Liyuan Kong +11 more
doaj
The reproductive dynamics of temperate amphibians: a review [PDF]
, 2007 The annual life cycle of pond breeding amphibians is characterized by periodical migrations between three critical habitats: breeding, post breeding - feeding - and hibernating.
Geltsch, Ioana Cristina +3 more
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Predicting coexistence of plants subject to a tolerance-competition trade-off
, 2013 Ecological trade-offs between species are often invoked to explain species coexistence in ecological communities. However, few mathematical models have been proposed for which coexistence conditions can be characterized explicitly in terms of a trade-off.
Etienne, Rampal S. +2 more
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TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Eukaryotic Adaptation to Years-Long Starvation Resembles that of Bacteria
iScience, 2019 Summary: The Growth Advantage in Stationary Phase (GASP) phenomenon, described in bacteria, reflects the genetic adaptation of bacteria to stress, including starvation, for a long time.
Tzemach Aouizerat +10 more
doaj
Competition between Bending and Internal Pressure Governs the Mechanics of Fluid Nanovesicles
ACS Nano, 2017 Nanovesicles (∼100 nm) are ubiquitous in cell biology and an important vector for drug delivery. Mechanical properties of vesicles are known to influence cellular uptake, but the mechanism by which deformation dynamics affect internalization is poorly ...
D. Vorselen +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Coexistence and relative abundance in annual plant assemblages: The roles of competition and colonization [PDF]
, 2002 Although an interspecific trade-off between competitive and colonizing ability can permit multispecies coexistence, whether this mechanism controls the structure of natural systems remains unresolved.
Levine, J.M., Rees, M.
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