Results 31 to 40 of about 498,731 (259)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Competitive analysis of online reviews using exploratory text mining

Tourism and Hospitality Management, 2016
Purpose – This paper explores the usefulness of analyzing text-based online reviews using text mining tools and visual analytics for SWOT Analysis, as applied to the hotel industry. These results can be used to develop competitive actions.
William J. Amadio , J. Drew Procaccino
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Analysis of the gypsum industry in Russia and methods of increasing the competitiveness of the organization on the example of JSC “Khabez Gypsum Plant”

Вестник Северо-Кавказского федерального университета
Introduction. The construction sector reacts to changes with a significant lag, slowing down longer than other industries during difficult periods and recovering longer after the crisis.
A. G. Chekalov, O. V. Berezhnaya
doaj   +1 more source

The Mutual Benchmarking Method for Smes’ Competitive Strategy Development

Foundations of Management, 2013
Competitive advantage is a relative feature, evaluated in respect of other competing enterprises. The gaining of sustainable competitive advantage is conditioned by knowledge of own performance and the results of the competitive environment.
Rostek Katarzyna
doaj   +1 more source

Analisis Strategi Peningkatan Daya Saing Madrasah Ibtidaiyah di Jember: Studi Multisitus

Tadris: Jurnal Pendidikan Islam, 2021
Madrasas/schools that have certain advantages become choices, while those that are mediocre are increasingly being abandoned. In this situation, an effective madrasah competitive strategy will determine its competitiveness and survival.
Mukniah, Zainal Abidin
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Improving the Competitive Ratio of the Online OVSF Code Assignment Problem

Algorithms, 2009
Online OVSF code assignment has an important application to wireless communications. Recently, this problem was formally modeled as an online problem, and performances of online algorithms have been analyzed by the competitive analysis. The previous best
Shuichi Miyazaki, Kazuya Okamoto
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source