Results 171 to 180 of about 697,227 (280)

Non-Competitive Binding of Isatuximab and Daratumumab to CD38: Implications for Targeted Therapy in Multiple Myeloma. [PDF]

Pharmaceutics
Osuna-Gómez R, López-Pardo J, Mulet M, Nomdedéu J, Cantó E, Ortin R, Cayuela ÁS, Ortiz MÀ, Guinart-Cuadra A, Vidal S.   +9 more
europepmc   +1 more source

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma. [PDF]

Nat Commun, 2021
Mahlokozera T, Patel B, Chen H, Desouza P, Qu X, Mao DD, Hafez D, Yang W, Taiwo R, Paturu M, Salehi A, Gujar AD, Dunn GP, Mosammaparast N, Petti AA, Yano H, Kim AH.   +16 more
europepmc   +1 more source

MnI‐Functionalized Covalent Organic Framework as Efficient Electrocatalyst for CO2 Reduction in a Catholyte‐Free Zero‐Gap Electrolyzer

Advanced Functional Materials, EarlyView.
This work demonstrates the successful integration of a phenanthroline‐based 2D COF with MnI catalytic sites into a catholyte‐free membrane‐electrode‐assembly cell for CO2 electroreduction. The crystalline COF actively suppresses Mn⁰–Mn⁰ dimerization, achieving a turnover frequency of 617 h⁻¹ at 2.8 V (full‐cell potential), and enabling stable operation.
Laura Spies, Marcos Eduardo G. Carmo, Gonçalves J. Marrenjo, Stephan Reuther, Patrick Ganswindt, Antonio Otavio T. Patrocinio, Thomas Bein, Osmando F. Lopes, Jenny Schneider   +8 more
wiley   +1 more source

Charge-based drug delivery to cartilage: Hydrophobic and not electrostatic interactions are the dominant cause of competitive binding of cationic carriers in synovial fluid. [PDF]

Acta Biomater, 2022
Vedadghavami A, He T, Zhang C, Amiji SM, Hakim B, Bajpayee AG.   +5 more
europepmc   +1 more source

Rational Fine‐Tuning of MOF Pore Metrics: Enhanced SO2 Capture and Sensing with Optimal Multi‐Site Interactions

Advanced Functional Materials, EarlyView.
A pore tuning strategy to amplify the multi‐site MOF‐SO2 interactions is proposed to achieve an enhanced trace SO2 capture and chemiresistive sensing in highly stable isostructural DMOFs by annelating benzene rings. This work provides a facile strategy to achieve tailor‐made stable MOF materials for specific multifunctional applications.
Shanghua Xing, Abdulrahman Mohabbat, István Boldog, Jens Möllmer, Marcus Lange, Yulyan Haiduk, Tobias Heinen, Vladimir Pankov, Oliver Weingart, Christoph Janiak   +9 more
wiley   +1 more source

SARS-CoV-2 nucleocapsid protein directly prevents cGAS-DNA recognition through competitive binding. [PDF]

Proc Natl Acad Sci U S A
Gutmann T, Kuster D, Hyman AA.
europepmc   +1 more source

Effects of size, cooperativity, and competitive binding on protein positioning on DNA. [PDF]

Biophys J, 2021
McCormack LS, Efremov AK, Yan J.
europepmc   +1 more source

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

Advanced Functional Materials, EarlyView.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya, Konda Reddy Kunduru, Krishanu Ghosal, Luna Rizik, Nofar Atari, Mahran Daifa, Neta Kutner, Bassma Khamaisi, Qi Wu, Simran Jindal, Merna Shaheen‐Mualim, Ranabir Majumder, Mahitosh Mandal, Michal Mandelboim, Shady Farah   +14 more
wiley   +1 more source

<i>CircUBAP2(9,12)</i> Inhibits Nasopharyngeal Carcinoma Invasion and Metastasis by Down-regulating <i>ZEB2</i> through Competitive Binding to AUF1. [PDF]

Research (Wash D C)
Fan C, Guo Z, Qu H, Yan Q, Wang D, Wang Y, Zhang S, Guo C, Zeng Z, Xiong W, Shi L.   +10 more
europepmc   +1 more source

Rapid screening of SARS-CoV-2 inhibitors via ratiometric fluorescence of RBD-ACE2 complexes in living cells by competitive binding. [PDF]

Acta Pharm Sin B, 2022
Miao L, Zhou W, Yan C, Zhang Y, Qiao Q, Zhou X, Chen Y, Wang G, Guo Z, Liu J, Piao H, Pan X, Yan M, Zhao W, Li G, Li Y, Xu Z.   +16 more
europepmc   +1 more source