Results 31 to 40 of about 5,445,100 (248)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Innovation, competitive strategy and MSME performance: a survey study on culinary SMEs in Indonesia during the COVID-19 pandemic

open access: yesBusiness: Theory and Practice, 2023
The aim of this research is to examine the relationship between innovation and performance in culinary sector MSME in Indonesia. This research also examines the mediating role of competitive strategies on the correlation of innovation in SME performance.
Cancelyn Shearin Pusung   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Mine is Bigger than Yours! Narcissism Predicts Biases in Perceived Head Size [PDF]

open access: yesStudia Psychologica, 2019
The expression big headed is often used to describe narcissists, however is it possible that this term signals a bias in how narcissists perceive themselves?
Minna Lyons   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Rate of Adoption of Strategic Marketing Planning (SMP) by the Libyan Commercial Banks (LCBs). An Exploratory Study [PDF]

open access: yesAthens Journal of Business & Economics, 2016
The purpose of this paper is to explore the foundations of SMP process in the LCBs being adopted in 2007. An interpretive approach was chosen to address the research questions posed.
Fthia Ramdan M. Abusafrita
doaj   +1 more source

DIGITAL SERVICES AS A TOOL FOR CREATING COMPETITIVE ADVANTAGE IN THE BANKING SECTOR IN NORTH MACEDONIA

open access: yesJournal of Liberty and International Affairs, 2021
In the last few years participants of the banking sector in North Macedonia are facing big competition as a result of the increased innovations between these participants.
Viktorija Stojkovski, Blagoj Nenovski
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Japanese Production Strategies and Competitive Success: Mazda's Quiet Revolution

open access: yes, 1995
The contribution of just-in-time manufacturing systems to competitive success - most notably in the case of Japanese companies, and specifically Toyota - has been widely recognised, but there has been less emphasis on the nature of these systems and ...
Pilkington, A.
core   +1 more source

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