Results 91 to 100 of about 1,236,352 (345)
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
FEBS Open Bio, EarlyView.PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley +1 more source
PSL Quarterly Review, 2002 Very few economic terms are used as much as competitiveness in economics. This article deals with the different meanings of competitiveness, at the level of a firm, at the level of the local area, and at the level of the country. It analyzes the problems of consistency among the available definitions and among the indicators used to measure ...
CELLINI, Roberto, SOCI A.
openaire +5 more sources
Assessing competitiveness: how firm-level data can help [PDF]
As policymakers refocus on growth, the ability to take a firm-level view is key to disentangling the various factors at the root of competitiveness, and thus to designing appropriate policies.
Carlo Altomonte +3 more
core +1 more source
Key role for inhibins in effective T cell activation, migration and Th17 differentiation
FEBS Open Bio, EarlyView.Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco +5 more
wiley +1 more source
Competitiveness of Bulgarian farms [PDF]
This paper suggests a holistic framework for assessing farm competitiveness, and analyses competitiveness of different type of Bulgarian farms. First, it present a new approach for assessing farm competitiveness defining farm competitiveness and its ...
Bachev, Hrabrin
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Assessing Destination Competitiveness: An Application to the Hot Springs Tourism Sector [PDF]
, 2006 This paper proposes a model to identify the factors determining the competitiveness of the hot springs tourism sector, with particular application to Taiwan.
King, Brian, Lee, Cheng-Fei
core +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Considerations about the Influence Factors on the Competitiveness of SME’s from Western Region of Romania [PDF]
There are many ways in which the firm competitiveness can be understood in the related literature. The purpose of this research is to undertake a better understanding of expectations and concerns of small and medium sized enterprises from Romanian ...
Bibu, Nicolae Aurelian +3 more
core +1 more source