Results 91 to 100 of about 2,267,242 (386)

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

FEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis   +6 more
wiley   +1 more source

Makers and clusters. Knowledge leaks in open innovation networks

Journal of Innovation & Knowledge, 2020
This paper aims at investigating the role of makers in open innovation networks by focusing on whether and how knowledge leaks occur in open innovation networks with makers. In the last years, makers have been widely recognized as conducive to innovation
Jessica D. Giusti, Fernando G. Alberti, Federica Belfanti   +2 more
doaj  

(Re)-structuring the Ceo’s compensation—the case of Israel

Economics and Business Review, 2020
The executive compensation issue continues to cause protest due to the increasing number of cases of an unjustifiably high level of pay. The main conflict arises from the misalignment of interests between the short-term expectations of the manager and ...
Mroczek-Dąbrowska Katarzyna, Shemesh Yaron   +1 more
doaj   +1 more source

New resonance approach to competitiveness interventions in lagging regions: the case of Ukraine before the armed conflict [PDF]

, 2017
Regional competitiveness is considered to be an alternative basis for the determination of regional interventions. However, the composite competitiveness indicator is quite sensitive to the weights of sub-indicators, no matter what methodology is being ...
Ahner, Ahner, Annoni, Annoni, Annoni, Annoni, Aranguren, Aranguren, Brussel, Brussel, Camagni, Camagni, Camagni, Camagni, Charles, Charles, Charnes, Charnes, Cooke, Cooke, Cооке, Cооке, Fernandez, Fernandez, Flood, Flood, Flood, Flood, Gábor, Gábor, Harmaakorpi, Harmaakorpi, Harman, Harman, Hellwig, Hellwig, Hollanders, Hollanders, Huggins, Huggins, Huggins, Huggins, Hugins, Hugins, Huovari, Huovari, Jackson, Jackson, Kiszová, Kiszová, Kuznets, Kuznets, London, London, Martin, Martin, Martin, Martin, Melecký, Melecký, Meyer, Meyer, Midelfart, Midelfart, Midgley, Midgley, Mingers, Mingers, Myrdal, Myrdal, Nevima, Nevima, Oliva, Oliva, Perroux, Perroux, Pessoa, Pessoa, Pluta, Pluta, Porter, Porter, Puga, Puga, Pооt, Pооt, Ramík, Ramík, Różańska, Różańska, Schaffer, Schaffer, Snieška, Snieška, Storper, Storper, Tetsuya, Tetsuya, UNDP, UNDP   +99 more
core   +2 more sources

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra, Sara Bernal, David Almenta, Josefina Pérez‐Blanco, Valle Camacho, Isabel Sala, Mª Belén Sánchez‐Saudinós, Jesús García Castro, Judit Selma‐González, Miguel Ángel Santos‐Santos, Álvaro Carbayo, Janina Turon‐Sans, Ricard Rojas‐Garcia, Daniel Alcolea, Juan Fortea, Alberto Lleó, Oriol Dols‐Icardo, Ignacio Illán‐Gala   +17 more
wiley   +1 more source

Review: Application and Prospective Discussion of Machine Learning for the Management of Dairy Farms

Animals, 2020
Dairy farmers use herd management systems, behavioral sensors, feeding lists, breeding schedules, and health records to document herd characteristics. Consequently, large amounts of dairy data are becoming available.
Marianne Cockburn
doaj   +1 more source

Evaluating competitiveness of airports - Airport competitiveness index [PDF]

The paper introduces a concept of airport competitiveness index. The index consists of numerous indicators grouped into four categories: market potential, infrastructure, charges and recent traffic results.
Grancay, Martin
core   +1 more source

Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Approximately half of patients with hereditary myopathies remain without a definitive genetic diagnosis after DNA next‐generation sequencing (NGS). Here, we implemented transcriptome analysis of muscle biopsies as a complementary diagnostic tool for patients with muscle disease but no definitive genetic diagnosis after exome ...
Alba Segarra‐Casas, Cristina Domínguez‐González, Daniel Natera‐de Benito, Solange Kapetanovic, Aurelio Hernández‐Laín, Berta Estévez‐Arias, Laura Llansó, Carlos Ortez, Cristina Jou, Itxaso Martí‐Carrera, Arístides López‐Márquez, Maria José Rodríguez, Laura González‐Mera, Velina Nedkova, Roberto Fernández‐Torrón, Benjamín Rodríguez‐Santiago, Cecília Jimenez‐Mallebrera, Raul Juntas‐Morales, Adolfo López‐de Munain, Jordi Surrallés, Andrés Nascimento, Eduard Gallardo, Montse Olivé, Pia Gallano, Lidia González‐Quereda   +24 more
wiley   +1 more source

Military Service Roles and ALS Among Veterans: A Matched Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT While military service is an established risk factor for amyotrophic lateral sclerosis (ALS), it remains unclear whether this association is linked to combat. We conducted a matched case–control study comparing 191 ALS patients who were veterans of the Israeli Defense Forces (IDF) with known military service type and 1910 matched controls. The
Asaf Honig, Roy Dayan, Amir Knaani, Hagai Levine, Marc Gotkine   +4 more
wiley   +1 more source

Basque Country cluster policy: the road of 25 years

Regional Studies, Regional Science, 2017
This paper addresses how cluster policy, particularly its management part, contributes to the processes of switching path dependency and escaping lock-ins in the old industrial regions.
Anastasiia Konstantynova
doaj   +1 more source