Biophysical insights into a cryptic ligand site in the hydrophobic core of human PCNA. [PDF]
Dispensa AN +8 more
europepmc +1 more source
Toward Fast Proton Shuttling in Acidic Oxygen Evolution Reaction
This review establishes proton transfer dynamics as a descriptor governing acidic OER activity, moving beyond the kinetic constraints derived from the proton coupled electron transfer. We discuss how deprotonation governs classical mechanisms, including adsorbate evolution mechanism (AEM), lattice oxygen mechanism (LOM) and oxide path mechanism (OPM ...
Ashish Gaur +3 more
wiley +1 more source
Rotation-Sensitive Feature Enhancement Network for Oriented Object Detection in Remote Sensing Images. [PDF]
Xu J, Huo H, Kang S, Mei A, Zhang C.
europepmc +1 more source
We introduce a capillary‐filtering‐based particle‐filling (CFPF) process that simultaneously forms vertical thermal pathways and electrical vias within µ‐pores. In situ microfluidic analysis reveals that capillary‐driven velocity gradients generate vorticity that governs µ‐platelet rotation and vertical alignment.
Yujin Mun +11 more
wiley +1 more source
Targeting cobra venom cytotoxin: a linear 40-mer ssDNA aptamer-based antivenom confers neutralisation potentials against cobra venom-induced cytotoxicity. [PDF]
Hiu JJ, Tan HS, Yap MKK.
europepmc +1 more source
Application of Ibuprofen Sodium Dihydrate for Thermochemical Energy Storage
Ibuprofen sodium dihydrate is introduced as a durable organic salt hydrate for low‐temperature thermochemical energy storage, operating within 60°C–110°C with high energy density. At the material level, it delivers ∼99.9% cycling efficiency over 150 cycles without deliquescence, enabled by a dual energy‐storage mechanism coupling dehydration and phase ...
Kavin Chakravarthy Thangaraj +10 more
wiley +1 more source
Development of Simple and Rapid Bead-Based Cytometric Immunoassays Using Superparamagnetic Hybrid Core-Shell Microparticles. [PDF]
Tobias C +5 more
europepmc +1 more source
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins +9 more
wiley +1 more source
Temporal attention amplifies stimulus information in fronto-cingulate cortex at an intermediate processing stage. [PDF]
Zhu J, Tian KJ, Carrasco M, Denison RN.
europepmc +1 more source

