Results 161 to 170 of about 37,010 (319)
Optimizing Real-Time Object Detection in a Multi-Neural Processing Unit System. [PDF]
Oh S, Kwon Y, Lee J.
europepmc +1 more source
A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria+5 more
wiley +1 more source
Exploring subthreshold processing for next-generation TinyAI. [PDF]
Nakhle F+3 more
europepmc +1 more source
These study underscores the pivotal role of neutrophil‐derived myeloid‐related protein 14 (MRP14) in the pathophysiology of acute ischemic stroke (AIS). MRP14 not only disrupts mitochondrial function, thereby inhibiting microglial phagocytosis of neutrophils, but also activates microglial pyroptosis, exacerbating neuroinflammation following AIS ...
Huijuan Jin+10 more
wiley +1 more source
Acceleration of the Relativistic Dirac-Kohn-Sham Method with GPU: A Pre-Exascale Implementation of BERTHA and PyBERTHA. [PDF]
Storchi L+6 more
europepmc +1 more source
HIGD1A maintains redox homeostasis in granulosa cells by modulating SOD2‐mediated dismutation of superoxide into H2O2, which is cleared by CAT and GPX enzymes. However, reduced HIGD1A activates the NF‐κB pathway and upregulates SOD2, leading to intracellular H2O2 accumulation due to impaired clearance.
Huiying Li+11 more
wiley +1 more source
A deep-learning-based consistency test approach for Earth system models on HPC systems. [PDF]
Yu Y+7 more
europepmc +1 more source
The encyclopedia of ceramics, compiled by W. P. Jervis, with much original matter now first published [PDF]
William Percival Jervis
openalex +1 more source
Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves+17 more
wiley +1 more source