Results 221 to 230 of about 48,799 (265)

POR structural domains important for the enzyme activity in R. capsulatus complementation system

Photosynthesis Research, 2002
NADPH:protochlorophyllide oxidoreductase (POR) catalyzes hydrogen transfer from NADPH to protochlorophyllide (PChlide) in the course of chlorophyll biosynthesis in photosynthetic organisms and is involved in the regulation of the development of photosynthetic apparatus in higher plants, algae and cyanobacteria. To approach molecular factors determining
Nikolai, Lebedev, Michael P, Timko
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Binding and activation of C4 and C3 on the red cell surface by non-complement enzymes

Molecular Immunology, 1988
We investigated the binding of C4 and C3 to red cell surfaces by non-complement enzymes. Cell bound C components were quantitated by a radioimmunoassay, the chain structure of bound components was analyzed by Western blotting and the hemolytic activity of bound components was determined.
M, Kirschfink, T, Borsos
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Enzymic activity of the second component of complement

Biochemistry, 1975
Isolated C2 and C2i preparations were able to hydrolyze a number of synthetic esters containing basic amino acids, among which N-alpha-acetylglycyl-L-lysine methyl ester (AcGlyLysOMe) was most susceptible. The cleaving activity was a property of the C2 molecule, since it correlated with the presence of C2 on analyses of C2 preparations by ...
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Ability of activated complement components to induce lysosomal enzyme release from macrophages

Nature, 1976
THE mechanism underlying chronic inflammation is of considerable medical importance both in temperate countries—where diseases such as rheumatoid arthritis are common—and in tropical countries—where various chronic inflammatory conditions cause much disease and disability.
H U, Schorlemmer, P, Davies, A C, Allison   +2 more
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Complement-dependent NADPH oxidase enzyme activation in renal ischemia/reperfusion injury

Free Radical Biology and Medicine, 2014
NADPH oxidase plays a central role in mediating oxidative stress during heart, liver, and lung ischemia/reperfusion injury, but limited information is available about NADPH oxidase in renal ischemia/reperfusion injury. Our aim was to investigate the activation of NADPH oxidase in a swine model of renal ischemia/reperfusion damage.
Simone S., Rascio F., Castellano G., Divella C., Chieti A., Ditonno P., Battaglia M., Crovace A., Staffieri F., Oortwijn B., Stallone G., Gesualdo L., Pertosa G., Grandaliano G.   +13 more
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Complement activation by antibodies to DNA in systemic lupus erythematosus measured by enzyme immunoassay

Clinical Immunology and Immunopathology, 1985
An enzyme immunoassay to detect complement-fixing antibodies to DNA (CF-antiDNA) was developed. Of SLE sera, 64% had these antibodies as did 6% of 50 rheumatoid arthritis and 3.2% of 93 normal human sera. The mean CF-antiDNA level was higher in the sera of SLE patients with renal disease than those SLE patients who had no renal disease (P less than 0 ...
R R, Valle, R B, Eaton, G, Schnneider, P H, Schur   +3 more
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Activated complement factor 3 is associated with liver fat and liver enzymes: the CODAM study

European Journal of Clinical Investigation, 2013
AbstractBackgroundThe complement system may be involved in the pathogenesis of alcoholic and nonalcoholic liver disease, although studies in humans are scarce. For this reason, we investigated whether circulating levels of activated complement factor 3 (C3a) were associated with hepatic steatosis and hepatocellular damage.Materials and methodsPlasma ...
Wlazlo, N., van Greevenbroek, M.M.J., Ferreira, I., Jansen, E.H.J.M., Feskens, E.J.M., van der Kallen, C.J.H., Schalkwijk, C.G., Bravenboer, B., Stehouwer, C.D.A.   +8 more
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Lysosomal Enzyme Release from Human Leukocytes: Mediation by the Alternate Pathway of Complement Activation

The Journal of Immunology, 1973
Abstract The alternate pathway of complement activation has recently assumed an important role in the mediation of inflammation and tissue injury. We have found that complement activated via this pathway interacts with human polymorphonuclear leukocytes (PMN) in the absence of particulates and stimulates the selective release of ...
I M, Goldstein, M, Brai, A G, Osler, G, Weissmann   +3 more
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Complement activation by PVA as measured by ELIFA (enzyme-linked immunoflow assay) for SC5b-9

Biomaterials, 2000
Polyvinyl alcohol (PVA) coated onto polyethylene (PE) tubes exposed to human serum for 1 hour at 37 degrees C resulted in the production of 1.03 +/- 0.04 microg/cm2 of the soluble form of the terminal membrane attack complex, SC5b-9. This was approximately 20 x that produced by the polyethylene. About one quarter of this total was found associated with
J P, Black, M V, Sefton
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Effect of muralytic enzyme degradation of streptococcal cell wall on complement activation in vivo and in vitro

Inflammation, 1987
Rats given a single intraperitoneal injection of an aqueous suspension of peptidoglycan-polysaccharide polymers derived from group A streptococcal cell wall (PG-APS) develop a severe, chronic, erosive arthritis which resembles human rheumatoid arthritis.
M J, Janusz, R A, Eisenberg, J H, Schwab
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