Facilitating crRNA Design by Integrating DNA Interaction Features of CRISPR‐Cas12a System
This study introduces a novel approach combining molecular dynamics simulations and neural network modeling to predict the Cas12a trans‐cleavage activity. By integrating sequence and molecular interaction features, prediction accuracy is enhanced, and identify key features affecting Cas12a trans‐cleavage activity.
Zhihao Yao+7 more
wiley +1 more source
Clinical Testing Guidance for Histoplasmosis in Patients With Community-acquired Pneumonia for Primary and Urgent Care Providers: Commentary on Enzyme Immunoassay Histoplasma Antibody Testing. [PDF]
Smith DJ+5 more
europepmc +1 more source
Detection of human IgG antibodies against <i>Mycoplasma genitalium</i> using a recombinant MG075 antigen. [PDF]
Kildemoes AMO+8 more
europepmc +1 more source
Targeting C1q prevents microglia-mediated synaptic removal in neuropathic pain. [PDF]
Yousefpour N+27 more
europepmc +1 more source
A novel thermostable lytic phage vB_EF_Enf3_CCASU-2024-3 against clinical Enterococcus faecium and Enterococcus faecalis. [PDF]
Amr RM+5 more
europepmc +1 more source
The burden of brucellosis in donkeys and its implications for public health and animal welfare: A systematic review and meta-analysis. [PDF]
Kithuka JM+3 more
europepmc +1 more source
Preliminary findings on the different gaze patterns on animal-based and human-based picture books in autistic children. [PDF]
An P, Wang C.
europepmc +1 more source
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