Results 301 to 310 of about 484,151 (372)

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang, Kexin He, Ruixue Huo, Weihan Li, Shan Zhang, Lu‐Ju Jiang, Hao Wu, Minhao Yu, Shu‐Heng Jiang, Junli Xue   +9 more
wiley   +1 more source

Real-time assessment of eye movements during reading in individuals with central vision loss using eye-tracking technology: A pilot study. [PDF]

J Optom
González-Vides L, Cañadas P, Gómez-Pedrero JA, Hernández-Verdejo JL.   +3 more
europepmc   +1 more source

Gradient Nanostructures and Machine Learning Synergy for Robust Quantitative Surface‐Enhanced Raman Scattering

Advanced Science, EarlyView.
A novel SERS platform using gradient nanostructures and machine learning is presented. Gradient nanostructures minimize fabrication variability and enhance spectral diversity. The ML model significantly improves quantification precision, robustness and reproducibility, reducing test MSE by 84.8% and increasing R2 by 61.2%, enabling reliable real‐world ...
Xiaoyu Zhao, Yuxia Wang, Yuting Liu, Xinyi Chen, Mingyu Cheng, Yaxin Wang, Jiahong Wen, Renxian Gao, Kun Zhang, Fengyi Zhang, Rufei Cui, Yongjun Zhang, Zengyao Wang, Bin Ai   +13 more
wiley   +1 more source

Eye tracking to support assessment of patients with prolonged disorder of consciousness - a case series. [PDF]

J Rehabil Med
Johansson J, Möller M, Franzon K, Stenberg J, Godbolt AK.   +4 more
europepmc   +1 more source

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

Some Human Anti-Glycan Antibodies Lack the Ability to Activate the Complement System. [PDF]

Antibodies (Basel)
Shilova N, Nokel A, Lipatnikov A, Khasbiullina N, Knirel Y, Baidakova L, Tuzikov A, Khaidukov S, Obukhova P, Henry S, Shoibonov B, Salimov E, Rieben R, Bovin N.   +13 more
europepmc   +1 more source

Knowledge Distillation for Molecular Property Prediction: A Scalability Analysis

Advanced Science, EarlyView.
This study explores the effectiveness of knowledge distillation (KD) for molecular property prediction using graph neural networks. By leveraging KD, student models achieve improved scalability and predictive accuracy across domain‐specific and cross‐domain molecular datasets.
Rahul Sheshanarayana, Fengqi You
wiley   +1 more source

Glaucoma Home Monitoring Using Online Circular Contrast Perimetry Over 6 Months: Performance and Patient Attitudes in the Developing World Setting. [PDF]

Clin Ophthalmol
Hoang TT, Mai TQ, Pham DT, Nguyen XT, Nguyen DA, Vu DT, Hoang HT, Skalicky SE.   +7 more
europepmc   +1 more source

Nucleic Acid‐Locked Smart Carrier for Photothermal/Chemotherapy‐Amplified Immunogenic Cell Death to Enhance Systemic Antitumor Efficacy

Advanced Science, EarlyView.
Multiple therapeutic modalities combined in a synergistic way that can modulate different immune axes are demonstrated potentially effective in boosting immunotherapy. A nucleic acid‐locked smart carrier (NASC) performed as an “all‐in‐one” nanoplatform is constructed for efficient eliciting chemo‐ and photothermal‐amplified immunogenic cell death to ...
Jiayang Zhang, Tianyu Gai, Jiwei Wang, Yucai Wu, Si‐Ming Zeng, Dongyuan Zhao, Wei Li   +6 more
wiley   +1 more source

An automatic sustained attention prediction (ASAP) method for infants and toddlers using wearable device signals. [PDF]

Sci Rep
Zhang Y, Martinez-Cedillo AP, Mason HT, Vuong QC, Garcia-de-Soria MC, Mullineaux D, Knight MI, Geangu E.   +7 more
europepmc   +1 more source