Results 91 to 100 of about 303,951 (335)

Epigenome‐wide association study, meta‐analysis, and multiscore profiling of whole blood in Parkinson's disease

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie, Manuela M. X. Tan, Maren Stolp Andersen, Mathias Toft, Lasse Pihlstrøm   +4 more
wiley   +1 more source

Evidence of blood–brain barrier dysfunction and CSF immunoglobulin synthesis in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives This study sought to evaluate proteomic, metabolomic, and immune signatures in the cerebrospinal fluid of individuals with Down Syndrome Regression Disorder (DSRD). Methods A prospective case–control study comparing proteomic, metabolomic, and immune profiles in individuals with DSRD was performed.
Jonathan D. Santoro, Neetha Paul Eduthan, Mellad M. Khoshnood, Saba Jafarpour, Natalie K. Boyd, Benjamin N. Vogel, Lina Nguyen, Lilia Kazerooni, Eleanor Britton, Hannah R. Lyford, Matthew D. Galbraith, Angela L. Rachubinski, Joaquin M. Espinosa   +12 more
wiley   +1 more source

Contour Completion Around a Fixation Point [PDF]

arXiv, 2012
The paper presents two edge grouping algorithms for finding a closed contour starting from a particular edge point and enclosing a fixation point. Both algorithms search a shortest simple cycle in \textit{an angularly ordered graph} derived from an edge image where a vertex is an end point of a contour fragment and an undirected arc is drawn between a ...
arxiv  

Detection of Leishmania infantum DNA in the non-parasitized lung of dogs with visceral leishmaniasis

BMC Veterinary Research, 2018
Background Despite the very low or absent parasitism in the lungs, the interstitial pneumonitis is a common lesion found in humans and dogs with visceral leishmaniasis.
Ricardo Goncalves, Soraia Oliveira Silva, Gregório Guilherme de Almeida, Carolina Carvalho de Souza, Wagner Luiz Tafuri, M. Norma Melo   +5 more
doaj   +1 more source

Brucella melitensis B115-based ELISA to unravel false positive serologic reactions in bovine brucellosis: a field study

BMC Veterinary Research, 2020
Background Brucellosis is a zoonosis whose incidence is not declining worldwide despite the global effort to control the disease. Accurate and precise diagnosis is a crucial step in any prophylaxis program but single tests to unequivocally detect animals
Adriana Trotta, Mariarosaria Marinaro, Margie Cirilli, Alessio Sposato, Rosanna Adone, Matteo Beverelli, Domenico Buonavoglia, Marialaura Corrente   +7 more
doaj   +1 more source

Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar, Arnold M. Evia, Mahir Tazwar, Sue E. Leurgans, David A. Bennett, Julie A. Schneider, Konstantinos Arfanakis   +6 more
wiley   +1 more source

Analytical performance evaluation of a rapid immunochromatographic test for the diagnosis of bovine brucellosis based on a recombinant BP26 protein [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Brucellosis is an important bacterial disease of global distribution with zoonotic potencial. Serological tests used in Brazil for diagnosis of bovine brucellosis, including the Rose Bengal test (RBT), 2-mercaptoethanol (2-ME), fluorescent polarization ...
P.G. Souza, P.A. Lima, P.M. Soares Filho, R.N. Etges, R.R. Nicolino, A.G. Viana, T.A. Paixão, R.T. Fujiwara, R.L. Santos   +8 more
doaj   +1 more source

Serological Studies on Twelve Species of Candida [PDF]

, 1971
The studies on the serology of Candida emphasize the fact that their antigenic structure is complicated. The results of the agglutination, precipitin reactions and complement fixation tests are confusing, contradictory and, so far, too impractical for ...
Fraser, Etta W.
core   +1 more source

Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan, Shravni Deshmukh, Mark Cummings, Aditi Doshi, Kourosh Rezania, Sally Freels, Gina Sawa   +6 more
wiley   +1 more source

Combining Sensitive Crossmatch Assays With Donor/Recipient Human Leukocyte Antigen Eplet Matching Predicts Living-Donor Kidney Transplant Outcome

Kidney International Reports, 2018
Introduction: Despite the different assays available for immune-risk stratification before living-donor kidney transplantation (LDKT), the precise type and number of tests to perform remain uncertain. Methods: In a cohort of 330 consecutive LDKT patients,
Maria Meneghini, Edoardo Melilli, Jaume Martorell, Ignacio Revuelta, Elisabet Rigol-Monzó, Anna Manonelles, Nuria Montero, David Cucchiari, Fritz Diekmann, Josep M. Cruzado, Salvador Gil-Vernet, Josep M. Grinyó, Oriol Bestard   +12 more
doaj