Results 51 to 60 of about 286,109 (296)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Entropy, 2022 For the science of autonomous human–machine systems, traditional causal-time interpretations of reality in known contexts are sufficient for rational decisions and actions to be taken, but not for uncertain or dynamic contexts, nor for building the best ...
William F. Lawless
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Ecology and Evolution, 2022 Although mate choice is expected to favor partners with advantageous genetic properties, the relative importance of genome‐wide characteristics, such as overall heterozygosity or kinship, versus specific loci, is unknown.
Rachel M. Petersen +3 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Comparative advantages and complementarity of Sino-US agricultural trade: An empirical analysis
Agricultural Economics (AGRICECON), 2011 By adopting the RCA, CMS, TCD, SI and TCI models, this paper has made an empirical analysis of the comparative advantages and complementarity of the agricultural trade between China and the United States in terms of sixteen major agricultural products ...
Chuanmin SHUAI, Xi WANG
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
broadinstitute/lincs-profiling-complementarity: Response to Reviewers
, 2022 We received three reviews for this paper, which required additional analyses, clarifying text in figures, and paper restructuring. This release captures all these changes. What's Changed [Response to Review] Add PCA supplementary figure by @gwaygenomics
Gregory Way +2 more
core +1 more source
Journal of Medicinal Chemistry, 2019 Electrostatic interactions between small molecules and their respective receptors are essential for molecular recognition and are also key contributors to the binding free energy.
M. Bauer, M. Mackey
semanticscholar +1 more source