Results 71 to 80 of about 146,013 (310)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Complementarity for Generalized Observables [PDF]
Physical Review Letters, 2002 We examine basic properties of complementarity by using the most general description of quantum observables as positive-operator measures. We show that, in general, two observables can be complementary or not depending on the measure of fluctuations adopted and that complementarity is not a symmetric relation.
openaire +4 more sources
The logic of complementarity [PDF]
, 2003 This paper is the sequel of a previous one where we have introduced a paraconsistent logic termed paraclassical logic to deal with 'complementary propositions'.
Krause, Décio, C. A. da Costa, Newton
core
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Volcanic caves: priorities for conserving the Azorean endemic troglobiont species
International Journal of Speleology, 2012 Azorean lava-tubes and volcanic pits adequately sampled for arthropod fauna were evaluated for species diversity and rarity. An iterative partial multiple regression analysis was performed to produce a multi-criteria index (Importance Value for Cave ...
Borges Paulo A.V. +9 more
doaj
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Reformulations of mathematical programming problems as linear complementarity problems
, 1982 A family of complementarity problems are defined as extensions of the well known Linear Complementarity Problem (LCP). These are (i.) Second Linear Complementarity Problem (SLCP) which is an LCP extended by introducing further equality restrictions and ...
Mitra, G, Judice, JJ
core
La Relación entre las Estrategias de Innovación: Coexistencia o Complementariedad
Journal of Technology Management & Innovation, 2009 This paper explores the relationships between internal R&D and external knowledge acquisition as business innovation strategies. Drawing on absorptive capacity framework (Cohen and Levinthal, 1990), we distinguish and empirically evaluate two possible ...
Jaider Manuel Vega Jurado +2 more
doaj +1 more source
Energies, 2020 The European demand for natural gas imports may change through the energy transition, which may affect natural gas exporters’ strategic behavior and consequently the natural gas prices.
Sina Heidari
doaj +1 more source