Results 81 to 90 of about 146,013 (310)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

The Fold complementarity problem and the order complementarity problem

open access: yesTopological Methods in Nonlinear Analysis, 1994
We consider the fold complementarity problem, which is one of the recent subjects in complementarity theory. It is a mathematical model used in economics in the study of distributive problems [\textit{A. Villar}, Operator theorems with applications to distributive problems and equilibrium models, Lecture Notes in Economics and Mathematical Systems 377,
openaire   +3 more sources

Algorithms and Environments for Complementarity

open access: yes, 2000
Complementarity problems arise in a wide variety of disciplines. Prototypical examples include theWardropian andWalrasian equilibrium models encountered in the engineering and economic disciplines and the first order optimality conditions for nonlinear
Munson, Todd
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Elasticities of Substitution and Complementarity [PDF]

open access: yes
This paper is a modern synthesis of the more than seventy years of literature on the elasticity of substitution. At times, authors, such as Mundlak, have provided syntheses of the literature but these often seem to be forgotten by later authors and ...
David I. Stern
core  

Universal complementarity between coherence and intrinsic concurrence for two-qubit states

open access: yesNew Journal of Physics, 2019
Entanglement and coherence are two essential quantum resources for quantum information processing. A natural question arises of whether there is a direct link between them.
Xiao-Gang Fan   +6 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

An enumerative method for the solution of linear complementarity problems

open access: yes, 1983
In this report an enumerative method for the solution of the Linear Complementarity Problem (LCP) is presented. This algorithm completely processes the LCP, and does not require any particular property of the LCP to apply.
Mitra, G, Judice, JJ
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy