Results 121 to 130 of about 3,270,422 (387)

Baboon endogenous virus genome. I. Restriction enzyme map of the unintegrated DNA genome of a primate retrovirus [PDF]

, 1980
A detailed restriction map was deduced for the genome of an endogenous retrovirus of a higher primate, that of baboon. The cleavage sites for 12 restriction enzymes were mapped. The unintegrated linear viral DNA intermediate that is produced by infection
Cohen, Maurice, Davidson, Norman, Gilden, Raymond V., McAllister, Robert M., Nicolson, Margery O., Rice, Nancy, Shure, Mavis   +6 more
core  

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Circulating HPV16 DNA may complement imaging assessment of early treatment efficacy in patients with HPV-positive oropharyngeal cancer

Journal of Translational Medicine, 2020
Background Early detection of treatment failure may improve clinical outcome and overall survival in patients with head and neck cancer after first-line treatment.
Tomasz W. Rutkowski, Agnieszka M. Mazurek, Mirosław Śnietura, Beata Hejduk, Maja Jędrzejewska, Barbara Bobek-Billewicz, Andrea d’Amico, Wojciech Pigłowski, Andrzej Wygoda, Krzysztof Składowski, Zofia Kołosza, Piotr Widłak   +11 more
doaj   +1 more source

A MOLECULAR MECHANISM OF MITOMYCIN ACTION: LINKING OF COMPLEMENTARY DNA STRANDS.

Proceedings of the National Academy of Sciences of the United States of America, 1963
and by The bacterial strains used included Escherichia coli strain B, Sarcina lutea strain ATCC-272, and the following Bacillus subtilis mutant lines:'0' " wild-type, the indole-requiring, the linked indole- and histidine-deficient (I-, H-), and a ...
V. Iyer, W. Szybalski
semanticscholar   +1 more source

A synthetic autonomous rotary nanomotor made from and fuelled by DNA [PDF]

arXiv, 2015
DNA nanostructures are made using synthetic DNA strands, the sequences of which are designed such that they will self-assemble into the desired form by hybridization of complementary domains. Various structures and devices have been presented, including DNA tweezers, nanorobots and a range of linear motors such as bipedal walkers.
arxiv  

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Femtomolar detection of nucleic acid based on functionalized gold nanoparticles

Nanophotonics, 2019
Deoxyribonucleic acid (DNA) detection is essential for the accurate and early diagnosis of a disease. In this study, a femtomolar DNA detection method based on the exploitation of the localized surface plasmon (LSP) resonance of gold nanoparticles (AuNPs)
Huang Jiaoqi, Zhang Yang, Lin Zhongquan, Liu Wei, Chen Xueping, Liu Yu, Tian Huiyan, Liu Qiqian, Gillibert Raymond, Spadavecchia Jolanda, Djaker Nadia, de la Chapelle Marc Lamy, Xiang Yang, Fu Weiling   +13 more
doaj   +1 more source

Entropy stabilizes floppy crystals of mobile DNA-coated colloids

, 2018
Grafting linkers with open ends of complementary single-stranded DNA makes a flexible tool to tune interactions between colloids,which facilitates the design of complex self-assembly structures. Recently, it has been proposed to coat colloids with mobile
Hu, Hao, Ni, Ran, Ruiz, Pablo Sampedro
core   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Enzyme-Linked Electrochemical Detection of PCR-Amplified Nucleotide Sequences Using Disposable Screen-Printed Sensors. Applications in Gene Expression Monitoring

Sensors, 2008
Electrochemical enzyme-linked techniques for sequence-specific DNA sensingare presented. These techniques are based on attachment of streptavidin-alkalinephosphatase conjugate to biotin tags tethered to DNA immobilized at the surface ofdisposable screen ...
Miroslav Fojta, Karel Vytras, Miloslava Fojtova, Petra Horaková-Brazdilova   +3 more
doaj