Results 21 to 30 of about 3,266,061 (366)

Statistical evaluation of the coding capacity of complementary DNA strands [PDF]

open access: greenNucleic Acids Research, 1984
Two independent methods are used to evaluate the protein-coding information content in different classes of DNA sequences. The first method allows to evaluate the statistical relevance of finding unidentified reading frames, longer than 100 codons, on both DNA strands of: a) 117 DNA sequences that code for 142 nuclear proteins; b) 39 stable RNA coding ...
Anna Tramontano   +6 more
openalex   +8 more sources

Rapid and Sensitive Detection of Severe Acute Respiratory Syndrome Coronavirus 2 in Label-Free Manner Using Micromechanical Sensors

open access: yesSensors, 2021
Coronavirus (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been identified as a deadly pandemic. The genomic analysis of SARS-CoV-2 is performed using a reverse transcription-polymerase chain reaction (RT-PCR)
Dalal A. Aloraini   +4 more
doaj   +1 more source

The isolation of plasmids containing dna complementary to messenger rna for variant surface glycoproteins of Trypanosoma brucei [PDF]

open access: green, 1980
We have isolated poly(A)+ RNA from four antigenic variants (117, 118, 121, 221) of one clone of Trypanosoma brucei. Translation of these poly(A)+ RNAs in a rabbit reticulocyte lysate gave rise to proteins that could be precipitated with antisera against ...
Jan H.J. Hoeijmakers   +4 more
openalex   +5 more sources

Synthesis and Evaluation of MGB Polyamide-Oligonucleotide Conjugates as Gene Expression Control Compounds

open access: yesJournal of Nucleic Acids, 2023
MGB polyamide-oligonucleotide conjugates ON 1-4 with linked MGB polyamides at the 2-exocyclic amino group of a guanine base using aminoalkyl linkers were synthesized and evaluated in terms of binding affinity for complementary DNA containing the MGB ...
Kazuo Kamaike   +13 more
doaj   +1 more source

A Brief Review of Graphene-Based Biosensors Developed for Rapid Detection of COVID-19 Biomarkers

open access: yesBiosensors, 2023
The prevalence of mutated species of COVID-19 antigens has provided a strong impetus for identifying a cost-effective, rapid and facile strategy for identifying the viral loads in public places.
Narendhar Chandrasekar   +7 more
doaj   +1 more source

Coding capacity of complementary DNA strands [PDF]

open access: yesNucleic Acids Research, 1981
A Fortran computer algorithm has been used to analyze the nucleotide sequence of several structural genes. The analysis performed on both coding and complementary DNA strands shows that whereas open reading frames shorter than 100 codons are randomly distributed on both DNA strands, open reading frames longer than 100 codons ("virtual genes") are ...
Casino A.   +5 more
openaire   +5 more sources

Cloning of human thyroglobulin complementary DNA [PDF]

open access: yesFEBS Letters, 1982
Journal Article ; Research Support, Non-U.S.
Brocas, Huguette   +3 more
openaire   +3 more sources

Mechanical separation of the complementary strands of DNA [PDF]

open access: yesProceedings of the National Academy of Sciences, 1997
We describe the mechanical separation of the two complementary strands of a single molecule of bacteriophage λ DNA. The 3′ and 5′ extremities on one end of the molecule are pulled progressively apart, and this leads to the opening of the double helix. The typical forces along the opening are in the range of 10–15 pN. The separation force signal is
François Heslot   +2 more
openaire   +3 more sources

Complementary DNA Libraries and Neurological Disease [PDF]

open access: yesArchives of Neurology, 1998
The DNA in our cell nuclei contains all the information necessary to direct our biological functions. The gene is 1 unit of such information that usually specifies the expression of 1 protein product. A detailed knowledge of each gene will enable us to understand disease at the molecular level.
Henry Furneaux, Benjamin Joseph
openaire   +2 more sources

Design strategy of antidote sequence for bivalent aptamer: Rapid neutralization of high‐anticoagulant thrombin‐binding bivalent DNA aptamer‐linked M08 with HD22

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2021
Background Bivalent thrombin‐binding aptamers (TBAs) have great potential for the treatment of thrombosis because they exhibit high anticoagulant activity, and their complementary single‐stranded DNA (ssDNA) sequences work as an antidote.
Toru Yoshitomi   +3 more
doaj   +1 more source

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