Results 91 to 100 of about 537,688 (292)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Player Monitoring in Indoor Team Sports: Concurrent Validity of Inertial Measurement Units to Quantify Average and Peak Acceleration Values

open access: yesFrontiers in Physiology, 2018
The increasing interest in assessing physical demands in team sports has led to the development of multiple sports related monitoring systems. Due to technical limitations, these systems primarily could be applied to outdoor sports, whereas an equivalent
Mareike Roell   +5 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Measuring gravitational lensing of the cosmic microwave background using cross correlation with large scale structure

open access: yes, 2012
We cross correlate the gravitational lensing map extracted from cosmic microwave background measurements by the Wilkinson Microwave Anisotropy Probe (WMAP) with the radio galaxy distribution from the NRAO VLA Sky Survey (NVSS) by using a quadratic ...
Aneesh V. Manohar   +7 more
core   +1 more source

High-Order Dual-Port Quasi-Absorptive Microstrip Coupled-Line Bandpass Filters [PDF]

open access: yes, 2020
In this article, we present the first demonstration of distributed and symmetrical all-band quasi-absorptive filters that can be designed to arbitrarily high orders.
Li, Y, Liu, X, Wu, X
core  

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